Reactome | p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10780546] ubiquitin-protein transferase activity of p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-GGA-2179276] SMURF2 monoubiquitinates SMAD3 - Gallus gallus
created	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
dbId	10780530
displayName	p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
hasComponent	[DefinedSet:R-GGA-2176487] p-T,2S-SMAD2,3:SMAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-GGA-178202] SMURF2 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm] - Homo sapiens
maxDepth	5
name	p-T-2S-SMAD2,3:SMAD4:SMURF2
producedByEvent	[Reaction:R-GGA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region - Gallus gallus
schemaClass	Complex
species	[Species:49591] Gallus gallus
stId	R-GGA-2179277
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-GGA-2179276] SMURF2 monoubiquitinates SMAD3
(physicalEntity)	[CatalystActivity:10780546] ubiquitin-protein transferase activity of p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]
(output)	[Reaction:R-GGA-2179274] SMURF2 binds SMAD3 phosphorylated in the linker region
(inferredTo)	[Complex:R-HSA-2179277] p-T-2S-SMAD2,3:SMAD4:SMURF2 [nucleoplasm]

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