Reactome | Collagen type XII degradation by MMP12

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Collagen type XII degradation by MMP12 Show undefined attributes

authored	[InstanceEdit:1442471] Jupe, S, 2011-07-12
catalystActivity	[CatalystActivity:2168030] metalloendopeptidase activity of MMP12 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:2168010] Jupe, S, 2012-03-23
dbId	2168046
displayName	Collagen type XII degradation by MMP12
edited	[InstanceEdit:2580335] Jupe, S, 2012-11-12
eventOf	[Pathway:R-HSA-1442490] Collagen degradation - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-2537499] Gelatin degradation by MMP19 - Homo sapiens [BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 - Homo sapiens
input	[Complex:R-HSA-2142915] Collagen type XII [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2168053] Extracellular matrix composition and remodeling in human abdominal aortic aneurysms: a proteomics approach
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Collagen type XII degradation by MMP12
orthologousEvent	[Reaction:R-CEL-2168046] Collagen type XII degradation by MMP12 - Caenorhabditis elegans [Reaction:R-GGA-2168046] Collagen type XII degradation by MMP12 - Gallus gallus [Reaction:R-XTR-2168046] Collagen type XII degradation by MMP12 - Xenopus tropicalis [Reaction:R-SSC-2168046] Collagen type XII degradation by MMP12 - Sus scrofa [Reaction:R-BTA-2168046] Collagen type XII degradation by MMP12 - Bos taurus [Reaction:R-CFA-2168046] Collagen type XII degradation by MMP12 - Canis familiaris [Reaction:R-MMU-2168046] Collagen type XII degradation by MMP12 - Mus musculus
output	[Complex:R-HSA-2470728] Cleaved collagen type XII [extracellular region]
releaseDate	2012-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2514803] Sorsa, Timo, 2012-10-08
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2168046
summation	[Summation:2168049] Collagen type XII is a member of the fibril-associated colla...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-2537499] Gelatin degradation by MMP19 [BlackBoxEvent:R-HSA-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
(hasEvent)	[Pathway:R-HSA-1442490] Collagen degradation

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