Reactome | Collagen type XII degradation by MMP12

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Collagen type XII degradation by MMP12 Show undefined attributes

catalystActivity	[CatalystActivity:10502154] metalloendopeptidase activity of MMP12 [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10502156
displayName	Collagen type XII degradation by MMP12
eventOf	[Pathway:R-SSC-1442490] Collagen degradation - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-SSC-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13 - Sus scrofa
inferredFrom	[Reaction:R-HSA-2168046] Collagen type XII degradation by MMP12 - Homo sapiens
input	[Complex:R-SSC-2142915] Collagen type XII [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Collagen type XII degradation by MMP12
output	[Complex:R-SSC-2470728] Cleaved collagen type XII [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49633] Sus scrofa
stId	R-SSC-2168046
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-SSC-1442490] Collagen degradation
(precedingEvent)	[BlackBoxEvent:R-SSC-1454757] Gelatin degradation by MMP1, 2, 3, 7, 8, 9, 12, 13
(inferredTo)	[Reaction:R-HSA-2168046] Collagen type XII degradation by MMP12

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