ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643765] N6-mAMP deaminase activity of ADAL:Zn [cytosol] Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates
category transition
compartment
created [InstanceEdit:2161188] D'Eustachio, P, 2012-03-08
crossReference
dbId 2161187
displayName ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine
edited
eventOf
input
isChimeric false
isInDisease false
isInferred false
literatureReference
modified [InstanceEdit:11879863] Wright, Adam, 2024-03-11
name
  • ADAL1 hydrolyzes N6-methyl-AMP to IMP and methylamine
  • N6-methyl-AMP(2-) + H2O + H+ => IMP(2-) + methylamine
  • Deamination of N6-methyl-AMP to form IMP
orthologousEvent
output
precedingEvent
releaseDate 2012-06-12
reviewStatus [ReviewStatus:9821382] five stars
reviewed
revised
schemaClass Reaction
species
stId R-HSA-2161187
summation
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