Reactome | MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine

Schema > Reaction > Entries

MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine Show undefined attributes

catalystActivity	[CatalystActivity:10277143] N6-methyl-AMP deaminase activity of MAPDA:Zn [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10277145
displayName	MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine
eventOf	[Pathway:R-CFA-74217] Purine salvage - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2161187] MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine - Homo sapiens
input	[SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-9731626] N(6)-methyl-AMP(2-) [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine N6-methyl-AMP(2-) + H2O + H+ => IMP(2-) + methylamine Deamination of N6-methyl-AMP to form IMP
output	[SimpleEntity:R-ALL-29602] IMP [cytosol] [SimpleEntity:R-ALL-9731652] methylamine [cytosol]
precedingEvent	[Reaction:R-CFA-9731632] NUDT1 hydrolyzes N6-methyl-ATP to N6-methyl-AMP - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-2161187
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-74217] Purine salvage
(inferredTo)	[Reaction:R-HSA-2161187] MAPDA hydrolyzes N6-methyl-AMP to IMP and methylamine

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