Reactome | 25(OH)D binds GC

authored	[InstanceEdit:378946] Jassal, Bijay, 2008-10-01
catalystActivity	[CatalystActivity:9959976] molecular carrier activity of GC [extracellular region]
category	transition
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:209970] Jassal, Bijay, 2008-01-08
dbId	209944
displayName	25(OH)D binds GC
edited	[InstanceEdit:352314] Jassal, B, 2008-06-02 10:50:11
eventOf	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-350186] CUBN binds GC:25(OH)D - Homo sapiens
input	[SimpleEntity:R-ALL-209906] 25(OH)D [extracellular region] [EntityWithAccessionedSequence:R-HSA-209886] GC [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:209916] A structural basis for the unique binding features of the human vitamin D-binding protein
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	25(OH)D binds GC
orthologousEvent	[Reaction:R-BTA-209944] 25(OH)D binds GC - Bos taurus [Reaction:R-GGA-209944] 25(OH)D binds GC - Gallus gallus [Reaction:R-XTR-209944] 25(OH)D binds GC - Xenopus tropicalis [Reaction:R-DRE-209944] 25(OH)D binds GC - Danio rerio [Reaction:R-SSC-209944] 25(OH)D binds GC - Sus scrofa [Reaction:R-CFA-209944] 25(OH)D binds GC - Canis familiaris [Reaction:R-RNO-209944] 25(OH)D binds GC - Rattus norvegicus [Reaction:R-MMU-209944] 25(OH)D binds GC - Mus musculus
output	[Complex:R-HSA-209892] GC:25(OH)D [extracellular region]
precedingEvent	[BlackBoxEvent:R-HSA-6807242] 25(OH)D translocates from ER membrane to extracellular region - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54 [InstanceEdit:9963238] Hill, David P, 2025-08-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-209944
summation	[Summation:209897] Vitamin D binding protein (GC aka DBP), a plasma protein, ca...
updateTrackers	[UpdateTracker:9783784] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v55:[add_removeInput, modifyText] [UpdateTracker:9780364] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v63:[modifyText] [UpdateTracker:9781800] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v60:[modifyText] [UpdateTracker:9964725] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v94:[removeCatalystActivity]

25(OH)D binds GC Show undefined attributes

Referrals

(updatedInstance)	[UpdateTracker:9783784] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v55:[add_removeInput, modifyText] [UpdateTracker:9780364] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v63:[modifyText] [UpdateTracker:9781800] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v60:[modifyText] [UpdateTracker:9964725] Update Tracker - [Reaction:209944] 25(OH)D binds GC - v94:[removeCatalystActivity]
(hasEvent)	[Pathway:R-HSA-196791] Vitamin D (calciferol) metabolism
(precedingEvent)	[Reaction:R-HSA-350186] CUBN binds GC:25(OH)D