Reactome | NF-kB is activated and signals survival

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NF-kB is activated and signals survival Show undefined attributes

authored	[InstanceEdit:188342] Nasi, Sergio, Annibali, D, 2006-10-10
created	[InstanceEdit:209557] Jassal, B, 2007-12-19 10:40:30
crossReference	[DatabaseIdentifier:12819573] BioModels Database:BIOMD0000000243 [DatabaseIdentifier:12819459] BioModels Database:BIOMD0000000407 [DatabaseIdentifier:12819431] BioModels Database:BIOMD0000000883 [DatabaseIdentifier:12819451] BioModels Database:BIOMD0000000477
dbId	209560
displayName	NF-kB is activated and signals survival
edited	[InstanceEdit:350668] Jassal, B, 2008-05-20 12:26:36
eventOf	[Pathway:R-HSA-193639] p75NTR signals via NF-kB - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-193703] IKKbeta is activated - Homo sapiens [Reaction:R-HSA-193705] IKKbeta phosphorylates IkB causing NF-kB to dissociate - Homo sapiens [Reaction:R-HSA-209536] IkB is ubiquitinated and degraded - Homo sapiens [Reaction:R-HSA-193691] NF-kB migrates to the nucleus and turns on transcription - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2017-06-22
literatureReference	[LiteratureReference:210952] NF-kappaB in the survival and plasticity of neurons
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	NF-kB is activated and signals survival
orthologousEvent	[Pathway:R-DRE-209560] NF-kB is activated and signals survival - Danio rerio [Pathway:R-DME-209560] NF-kB is activated and signals survival - Drosophila melanogaster [Pathway:R-GGA-209560] NF-kB is activated and signals survival - Gallus gallus [Pathway:R-XTR-209560] NF-kB is activated and signals survival - Xenopus tropicalis [Pathway:R-SSC-209560] NF-kB is activated and signals survival - Sus scrofa [Pathway:R-BTA-209560] NF-kB is activated and signals survival - Bos taurus [Pathway:R-CFA-209560] NF-kB is activated and signals survival - Canis familiaris [Pathway:R-RNO-209560] NF-kB is activated and signals survival - Rattus norvegicus [Pathway:R-MMU-209560] NF-kB is activated and signals survival - Mus musculus
releaseDate	2008-06-30
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:350667] Friedman, WJ, 2008-05-20 12:23:46 [InstanceEdit:351795] Chao, MV, 2008-05-28 09:46:01
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-209560
summation	[Summation:209547] Upon activation in response to NGF, NF-kB moves to the nucle...
updateTrackers	[UpdateTracker:9780999] Update Tracker - [Pathway:209560] NF-kB is activated and signals survival - v61:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9780999] Update Tracker - [Pathway:209560] NF-kB is activated and signals survival - v61:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-193639] p75NTR signals via NF-kB