Reactome | Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA

Schema > Reaction > Entries

Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA Show undefined attributes

authored	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
catalystActivity	[CatalystActivity:548822] fatty acid elongase activity of ELOVL2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:17957] endoplasmic reticulum lumen [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:2046086] Garapati, P V, 2012-01-11
dbId	2046090
displayName	Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA
edited	[InstanceEdit:2046103] Garapati, P V, 2012-01-11
eventOf	[Pathway:R-HSA-2046106] alpha-linolenic acid (ALA) metabolism - Homo sapiens
followingEvent	[Reaction:R-HSA-2046099] Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-2046057] DPA-CoA [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046066] Malonyl-CoA [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113601] NADPH [endoplasmic reticulum lumen]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:2045979] Elongation of long-chain fatty acids [LiteratureReference:2045974] The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA
orthologousEvent	[Reaction:R-PFA-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Plasmodium falciparum [Reaction:R-DDI-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Dictyostelium discoideum [Reaction:R-DME-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Drosophila melanogaster [Reaction:R-GGA-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Gallus gallus [Reaction:R-XTR-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Xenopus tropicalis [Reaction:R-DRE-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Danio rerio [Reaction:R-SSC-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Sus scrofa [Reaction:R-BTA-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Bos taurus [Reaction:R-CFA-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Canis familiaris [Reaction:R-RNO-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Rattus norvegicus [Reaction:R-MMU-2046090] Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-159751] CO2 [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-162743] CoA-SH [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-113519] H2O [endoplasmic reticulum lumen] 2 × [SimpleEntity:R-ALL-113564] NADP+ [endoplasmic reticulum lumen] [SimpleEntity:R-ALL-2046065] TPA-CoA [endoplasmic reticulum lumen]
precedingEvent	[Reaction:R-HSA-2046100] Elongation of eicosapentaenoyl-CoA to docosapentaenoyl-CoA - Homo sapiens
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-2046090
summation	[Summation:2045920] Docosapentaenoyl-CoA is elongated to tetracosapentaenoyl-CoA...

Referrals

(hasEvent)	[Pathway:R-HSA-2046106] alpha-linolenic acid (ALA) metabolism
(precedingEvent)	[Reaction:R-HSA-2046099] Desaturation of tetracosapentaenoyl-CoA to tetracosahexaenoyl-CoA