Reactome | Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA

Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA

Stable Identifier

R-HSA-2046090

Type

Reaction [transition]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen, endoplasmic reticulum membrane

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Elongation of docosapentaenoyl-CoA to tetracosapentaenoyl-CoA

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Docosapentaenoyl-CoA is elongated to tetracosapentaenoyl-CoA (9,12,15,18,21-24:5(n-3)) by the enzyme ELOVL2.

Literature References

PubMed ID	Title	Journal	Year
14636670	Elongation of long-chain fatty acids Leonard, AE, Pereira, SL, Sprecher, H, Huang, YS	Prog Lipid Res	2004
1834642	The metabolism of 7,10,13,16,19-docosapentaenoic acid to 4,7,10,13,16,19-docosahexaenoic acid in rat liver is independent of a 4-desaturase Voss, A, Reinhart, M, Sankarappa, S, Sprecher, H	J Biol Chem	1991