Reactome | p-8Y-FGFR2 K660M [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

p-8Y-FGFR2 K660M [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2033310] Activated FGFR2 K660M mutant [plasma membrane] - Homo sapiens [Complex:R-HSA-2033310] Activated FGFR2 K660M mutant [plasma membrane] - Homo sapiens
created	[InstanceEdit:2033299] Rothfels, K, 2012-01-09
crossReference	[DatabaseIdentifier:12021031] Mondo:0002974 [DatabaseIdentifier:2033257] COSMIC:COSV60656279
dbId	2033300
disease	[Disease:1500689] cancer [Disease:1614672] cervical cancer
displayName	p-8Y-FGFR2 K660M [plasma membrane]
endCoordinate	821
hasModifiedResidue	[ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2029853] O4'-phospho-L-tyrosine at unknown position [ReplacedResidue:1637903] L-lysine 660 replaced with L-methionine
inDisease	true
inferredFrom	[EntityWithAccessionedSequence:R-HSA-2032959] p-6Y-FGFR3 K650M [plasma membrane] - Homo sapiens
literatureReference	[LiteratureReference:1637882] Drug-sensitive FGFR2 mutations in endometrial carcinoma
maxDepth	1
modified	[InstanceEdit:5649608] Rothfels, Karen, 2014-11-20
name	p-8Y-FGFR2 K660M
referenceEntity	[ReferenceGeneProduct:uniprot:P21802] UniProt:P21802 FGFR2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2033300
startCoordinate	22
updateTrackers	[UpdateTracker:9891221] Update Tracker - [EntityWithAccessionedSequence:2033300] p-8Y-FGFR2 K660M [plasma membrane] - v52:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9891221] Update Tracker - [EntityWithAccessionedSequence:2033300] p-8Y-FGFR2 K660M [plasma membrane] - v52:[modifyName]
(hasComponent)	[Complex:R-HSA-2033310] Activated FGFR2 K660M mutant [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-2032959] p-6Y-FGFR3 K650M [plasma membrane]