Reactome | p-6Y-FGFR3b G697C [plasma membrane]

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p-6Y-FGFR3b G697C [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2033340] Activated FGFR3b G967C [plasma membrane] - Homo sapiens [Complex:R-HSA-2033340] Activated FGFR3b G967C [plasma membrane] - Homo sapiens
created	[InstanceEdit:2032968] Rothfels, K, 2012-01-08
crossReference	[DatabaseIdentifier:12020747] Mondo:0010150 [DatabaseIdentifier:2032970] COSMIC:COSV53390947
dbId	2032969
disease	[Disease:1248679] head and neck squamous cell carcinoma [Disease:1500689] cancer
displayName	p-6Y-FGFR3b G697C [plasma membrane]
endCoordinate	808
hasModifiedResidue	[ModifiedResidue:190954] O4'-phospho-L-tyrosine at 579 [ModifiedResidue:190955] O4'-phospho-L-tyrosine at 649 [ModifiedResidue:190386] O4'-phospho-L-tyrosine at 650 [ModifiedResidue:190953] O4'-phospho-L-tyrosine at 726 [ModifiedResidue:190952] O4'-phospho-L-tyrosine at 762 [ModifiedResidue:1307902] O4'-phospho-L-tyrosine at 772 [ReplacedResidue:2018742] glycine 697 replaced with L-cysteine
inDisease	true
literatureReference	[LiteratureReference:2032920] Constitutive activating mutation of the FGFR3b in oral squamous cell carcinomas
maxDepth	1
modified	[InstanceEdit:5649603] Rothfels, Karen, 2014-11-20
name	p-6Y-FGFR3b G697C p-6XY-FGFR3-2 G697C
referenceEntity	[ReferenceIsoform:uniprot:P22607-2] UniProt:P22607-2 FGFR3
referenceType	ReferenceIsoform
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2032969
startCoordinate	23
summation	[Summation:2032971] Note that residue G697C is numbered according to the FGFR3c ...
updateTrackers	[UpdateTracker:9891366] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v52:[modifyName] [UpdateTracker:9881455] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9891366] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v52:[modifyName] [UpdateTracker:9881455] Update Tracker - [EntityWithAccessionedSequence:2032969] p-6Y-FGFR3b G697C [plasma membrane] - v45:[addName]
(hasComponent)	[Complex:R-HSA-2033340] Activated FGFR3b G967C [plasma membrane]

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