Reactome | p-6Y-FGFR3 G382D [plasma membrane]

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p-6Y-FGFR3 G382D [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2033323] Activated FGFR3 G382D mutant [plasma membrane] - Homo sapiens [Complex:R-HSA-2033323] Activated FGFR3 G382D mutant [plasma membrane] - Homo sapiens
created	[InstanceEdit:2032949] Rothfels, K, 2012-01-08
crossReference	[DatabaseIdentifier:12020798] Mondo:0009693 [DatabaseIdentifier:2032951] COSMIC:COSV53427487
dbId	2032950
disease	[Disease:1500689] cancer [Disease:1614388] multiple myeloma
displayName	p-6Y-FGFR3 G382D [plasma membrane]
endCoordinate	806
hasModifiedResidue	[ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ModifiedResidue:2032947] O4'-phospho-L-tyrosine at unknown position [ReplacedResidue:2018739] glycine 382 replaced with L-aspartic acid
inDisease	true
literatureReference	[LiteratureReference:2032925] Deregulated FGFR3 mutants in multiple myeloma cell lines with t(4;14): comparative analysis of Y373C, K650E and the novel G384D mutations
maxDepth	1
modified	[InstanceEdit:5649594] Rothfels, Karen, 2014-11-20
name	p-6Y-FGFR3 G382D
referenceEntity	[ReferenceGeneProduct:uniprot:P22607] UniProt:P22607 FGFR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2032950
startCoordinate	23
updateTrackers	[UpdateTracker:9890558] Update Tracker - [EntityWithAccessionedSequence:2032950] p-6Y-FGFR3 G382D [plasma membrane] - v52:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9890558] Update Tracker - [EntityWithAccessionedSequence:2032950] p-6Y-FGFR3 G382D [plasma membrane] - v52:[modifyName]
(hasComponent)	[Complex:R-HSA-2033323] Activated FGFR3 G382D mutant [plasma membrane]

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