Reactome | 11xCbxE-PROS1 [extracellular region]

Schema > EntityWithAccessionedSequence > Entries

11xCbxE-PROS1 [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-HSA-9669957] FVIIIa:FIXa:PROS1 [plasma membrane] - Homo sapiens [Complex:R-HSA-981655] C4 binding protein:protein S [plasma membrane] - Homo sapiens [Complex:R-HSA-9931610] TFPI?:FV intermediate:PROS1 [extracellular region] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9669959] Factor IXa binds protein S - Homo sapiens [Reaction:R-HSA-981665] C4b binding protein binds Protein S - Homo sapiens [Reaction:R-HSA-9931628] TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1 - Homo sapiens
created	[InstanceEdit:202769] de Bono, B, 2007-11-11 17:35:21
dbId	202772
displayName	11xCbxE-PROS1 [extracellular region]
endCoordinate	676
hasModifiedResidue	[ModifiedResidue:140994] L-gamma-carboxyglutamic acid at 77 [ModifiedResidue:140995] L-gamma-carboxyglutamic acid at 73 [ModifiedResidue:140996] L-gamma-carboxyglutamic acid at 70 [ModifiedResidue:140997] L-gamma-carboxyglutamic acid at 67 [ModifiedResidue:140998] L-gamma-carboxyglutamic acid at 66 [ModifiedResidue:140999] L-gamma-carboxyglutamic acid at 61 [ModifiedResidue:141000] L-gamma-carboxyglutamic acid at 60 [ModifiedResidue:141001] L-gamma-carboxyglutamic acid at 57 [ModifiedResidue:141002] L-gamma-carboxyglutamic acid at 55 [ModifiedResidue:141003] L-gamma-carboxyglutamic acid at 48 [ModifiedResidue:349719] L-gamma-carboxyglutamic acid at 47
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-202772] Pros1 [extracellular region] - Mus musculus [EntityWithAccessionedSequence:R-RNO-202772] Pros1 [extracellular region] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-202772] PROS1 [extracellular region] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-202772] PROS1 [extracellular region] - Bos taurus [EntityWithAccessionedSequence:R-SSC-202772] PROS1 [extracellular region] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-202772] pros1 [extracellular region] - Danio rerio [EntityWithAccessionedSequence:R-XTR-202772] pros1 [extracellular region] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-202772] PROS1 [extracellular region] - Gallus gallus
literatureReference	[LiteratureReference:141005] Characterization of protein S, a gamma-carboxyglutamic acid containing protein from bovine and human plasma
maxDepth	1
memberOf	[DefinedSet:R-HSA-202771] TAM receptor ligands [extracellular region] - Homo sapiens [DefinedSet:R-HSA-481033] Platelet alpha granule contents [extracellular region] - Homo sapiens
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	11xCbxE-PROS1 protein S
referenceEntity	[ReferenceGeneProduct:uniprot:P07225] UniProt:P07225 PROS1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-202772
startCoordinate	42
updateTrackers	[UpdateTracker:9886696] Update Tracker - [EntityWithAccessionedSequence:202772] 11xCbxE-PROS1 [extracellular region] - v45:[addName] [UpdateTracker:9867293] Update Tracker - [EntityWithAccessionedSequence:202772] 11xCbxE-PROS1 [extracellular region] - v25:[addHasModifiedResidue]

Referrals

(updatedInstance)	[UpdateTracker:9886696] Update Tracker - [EntityWithAccessionedSequence:202772] 11xCbxE-PROS1 [extracellular region] - v45:[addName] [UpdateTracker:9867293] Update Tracker - [EntityWithAccessionedSequence:202772] 11xCbxE-PROS1 [extracellular region] - v25:[addHasModifiedResidue]
(input)	[Reaction:R-HSA-9931628] TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1 [Reaction:R-HSA-9669959] Factor IXa binds protein S [Reaction:R-HSA-981665] C4b binding protein binds Protein S
(hasMember)	[DefinedSet:R-HSA-202771] TAM receptor ligands [extracellular region] [DefinedSet:R-HSA-481033] Platelet alpha granule contents [extracellular region]
(hasComponent)	[Complex:R-HSA-9931610] TFPI?:FV intermediate:PROS1 [extracellular region] [Complex:R-HSA-9669957] FVIIIa:FIXa:PROS1 [plasma membrane] [Complex:R-HSA-981655] C4 binding protein:protein S [plasma membrane]
(activeUnit)	[NegativeRegulation:9669964] Negative regulation by 'FVIIIa:FIXa:PROS1 [plasma membrane]'

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