Reactome | Negative regulation by 'Cyclophilin A:Cyclosporin A [cytosol]'

Schema > NegativeRegulation > Entries

created	[InstanceEdit:2026006] May, B, 2011-12-20
dbId	2026015
displayName	Negative regulation by 'Cyclophilin A:Cyclosporin A [cytosol]'
modified	[InstanceEdit:9608020] Wu, G, 2018-05-08
regulatedEntity	[BlackBoxEvent:R-HSA-2025882] Calcineurin dephosphorylates NFATC1,2,3 - Homo sapiens
regulator	[Complex:R-HSA-2026008] Cyclophilin A:Cyclosporin A [cytosol]
schemaClass	NegativeRegulation
stId	R-HSA-2026015

(regulation)	[RegulationReference:9642060] Negative regulation by 'Cyclophilin A:Cyclosporin A [cytosol]' Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
(regulatedBy)	[BlackBoxEvent:R-HSA-2025882] Calcineurin dephosphorylates NFATC1,2,3

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