Reactome | Translocation of ZAP-70 to Immunological synapse

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Translocation of ZAP-70 to Immunological synapse Show undefined attributes

authored	[InstanceEdit:211006] Rudd, C.E., de Bono, B, Garapati, P V, 2008-01-24 15:53:10
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:202431] Garapati, P V, 2007-10-29 15:18:45
crossReference	[DatabaseIdentifier:12819469] BioModels Database:BIOMD0000000724
dbId	202430
displayName	Translocation of ZAP-70 to Immunological synapse
eventOf	[Pathway:R-HSA-202403] TCR signaling - Homo sapiens
figure	[Figure:9689479] /figures/static/R-HSA-202430.svg
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-202344] Recruitment of ZAP-70 to phosphorylated ITAMs - Homo sapiens [Reaction:R-HSA-202168] Phosphorylation of ZAP-70 by Lck - Homo sapiens [Reaction:R-HSA-8855381] PTPN22 dephosphorylates ZAP70 - Homo sapiens [Reaction:R-HSA-202174] Activation of ZAP-70 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2020-06-17
literatureReference	[LiteratureReference:202588] T cell antigen-receptor signal transduction
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Translocation of ZAP-70 to Immunological synapse
orthologousEvent	[Pathway:R-CFA-202430] Translocation of ZAP-70 to Immunological synapse - Canis familiaris [Pathway:R-XTR-202430] Translocation of ZAP-70 to Immunological synapse - Xenopus tropicalis [Pathway:R-SSC-202430] Translocation of ZAP-70 to Immunological synapse - Sus scrofa [Pathway:R-BTA-202430] Translocation of ZAP-70 to Immunological synapse - Bos taurus [Pathway:R-RNO-202430] Translocation of ZAP-70 to Immunological synapse - Rattus norvegicus [Pathway:R-MMU-202430] Translocation of ZAP-70 to Immunological synapse - Mus musculus
releaseDate	2008-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:214481] Trowsdale, J, 2008-02-26 12:02:59
revised	[InstanceEdit:8870543] Stanford, Stephanie, 2016-05-10 [InstanceEdit:8870542] Bottini, Nunzio, 2016-05-10
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-202430
summation	[Summation:202650] The dual phosphorylated ITAMs recruit SYK kinase ZAP70 via t...
updateTrackers	[UpdateTracker:9777036] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v73:[modifyText] [UpdateTracker:9789089] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v38:[addLiteratureReference] [UpdateTracker:9783022] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v57:[addHasEvent]

Referrals

(updatedInstance)	[UpdateTracker:9777036] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v73:[modifyText] [UpdateTracker:9789089] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v38:[addLiteratureReference] [UpdateTracker:9783022] Update Tracker - [Pathway:202430] Translocation of ZAP-70 to Immunological synapse - v57:[addHasEvent]
(hasEvent)	[Pathway:R-HSA-202403] TCR signaling