Reactome | Translocation of ZAP-70 to Immunological synapse

Schema > Pathway > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10447035] Weiser, Joel, 2026-03-16
dbId	10556905
displayName	Translocation of ZAP-70 to Immunological synapse
eventOf	[Pathway:R-SSC-202403] TCR signaling - Sus scrofa
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-SSC-202168] Phosphorylation of ZAP-70 by Lck - Sus scrofa [Reaction:R-SSC-8855381] PTPN22 dephosphorylates ZAP70 - Sus scrofa [Reaction:R-SSC-202174] Activation of ZAP-70 - Sus scrofa
inferredFrom	[Pathway:R-HSA-202430] Translocation of ZAP-70 to Immunological synapse - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Translocation of ZAP-70 to Immunological synapse
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:49633] Sus scrofa
stId	R-SSC-202430
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-SSC-202403] TCR signaling
(inferredTo)	[Pathway:R-HSA-202430] Translocation of ZAP-70 to Immunological synapse

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