Reactome | CSNK2-mediated phosphorylation of DVL

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CSNK2-mediated phosphorylation of DVL Show undefined attributes

authored	[InstanceEdit:4415000] Rothfels, K, 2013-08-23
catalystActivity	[CatalystActivity:201699] protein serine/threonine kinase activity of Casein kinase II [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:201703] Matthews, L, 2007-09-10 21:56:08
dbId	201717
displayName	CSNK2-mediated phosphorylation of DVL
edited	[InstanceEdit:201675] Matthews, L, 2007-09-04 11:49:29 [InstanceEdit:4655138] Gillespie, ME, 2013-10-02
eventOf	[Pathway:R-HSA-201688] WNT mediated activation of DVL - Homo sapiens
followingEvent	[Reaction:R-HSA-3772435] WNT signaling stimulates CSNK1-dependent phosphorylation of DVL - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-HSA-201725] DVL [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3772336] Dishevelled phosphorylation, subcellular localization and multimerization regulate its role in early embryogenesis [LiteratureReference:3772361] Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases [LiteratureReference:3772328] Casein kinase 2 associates with and phosphorylates dishevelled [LiteratureReference:3772372] The dishevelled protein is modified by wingless signaling in Drosophila [LiteratureReference:3772345] Human dishevelled genes constitute a DHR-containing multigene family
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	CSNK2-mediated phosphorylation of DVL
orthologousEvent	[Reaction:R-CEL-201717] CSNK2-mediated phosphorylation of DVL - Caenorhabditis elegans [Reaction:R-DME-201717] CSNK2-mediated phosphorylation of DVL - Drosophila melanogaster [Reaction:R-DRE-201717] CSNK2-mediated phosphorylation of DVL - Danio rerio [Reaction:R-SSC-201717] CSNK2-mediated phosphorylation of DVL - Sus scrofa [Reaction:R-BTA-201717] CSNK2-mediated phosphorylation of DVL - Bos taurus [Reaction:R-CFA-201717] CSNK2-mediated phosphorylation of DVL - Canis familiaris [Reaction:R-RNO-201717] CSNK2-mediated phosphorylation of DVL - Rattus norvegicus [Reaction:R-MMU-201717] CSNK2-mediated phosphorylation of DVL - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-HSA-201689] p-DVL [cytosol]
releaseDate	2014-03-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5251465] Rajakulendran, Nishani, 2014-01-22 [InstanceEdit:5323527] van Amerongen, R, 2014-02-14 [InstanceEdit:5368564] Kikuchi, Akira, 2014-04-22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-201717
summation	[Summation:201682] DVL proteins from Drosophila, Xenopus, mouse and human cells...

Referrals

(hasEvent)	[Pathway:R-HSA-201688] WNT mediated activation of DVL
(precedingEvent)	[Reaction:R-HSA-3772435] WNT signaling stimulates CSNK1-dependent phosphorylation of DVL