Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction

category binding
compartment
created [InstanceEdit:200953] Gillespie, ME, 2007-07-26 04:51:49
crossReference
dbId 200952
disease
displayName Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction
eventOf
input
isInDisease true
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name
  • Nef binds a ternary complex comprising DOCK2 guanine nucleotide exchange factor for small Rho-family GTPase Rac, its cofactor ELMO1, and Rac, and activates Rac through this interaction
output
relatedSpecies
releaseDate 2005-09-26
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass Reaction
species
stId R-HSA-200952
summation
updateTrackers
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