Reactome | TLR3 [endosome membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:74700] endosome membrane
componentOf	[Complex:R-HSA-167985] viral dsRNA :TLR3 [endosome membrane] - Homo sapiens [Complex:R-HSA-167985] viral dsRNA :TLR3 [endosome membrane] - Homo sapiens [Complex:R-HSA-9836752] TLR3:RSV copy-back dsRNA [endosome membrane] - Homo sapiens [Complex:R-HSA-9836752] TLR3:RSV copy-back dsRNA [endosome membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-168092] Viral dsRNA binds the Toll-Like Receptor 3 (TLR3) - Homo sapiens [Reaction:R-HSA-168092] Viral dsRNA binds the Toll-Like Receptor 3 (TLR3) - Homo sapiens [Reaction:R-HSA-9836763] RSV dsRNA binds TLR3 - Homo sapiens [Reaction:R-HSA-9836763] RSV dsRNA binds TLR3 - Homo sapiens
created	[InstanceEdit:2000340] Shamovsky, V, 2011-11-21
dbId	2000341
displayName	TLR3 [endosome membrane]
endCoordinate	904
inDisease	false
maxDepth	1
name	TLR3 Toll-like Receptor 3
referenceEntity	[ReferenceGeneProduct:uniprot:O15455] UniProt:O15455 TLR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-2000341
startCoordinate	24

(normalEntity)	[EntityFunctionalStatus:5602581] loss_of_function of TLR3 variants [endosome membrane]
(hasComponent)	[Complex:R-HSA-9836752] TLR3:RSV copy-back dsRNA [endosome membrane] [Complex:R-HSA-167985] viral dsRNA :TLR3 [endosome membrane]
(input)	[Reaction:R-HSA-9836763] RSV dsRNA binds TLR3 [Reaction:R-HSA-168092] Viral dsRNA binds the Toll-Like Receptor 3 (TLR3)

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