Reactome | TCR complex interacts with peptide antigen-presenting MHC Class I

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TCR complex interacts with peptide antigen-presenting MHC Class I Show undefined attributes

authored	[InstanceEdit:198923] de Bono, B, 2007-07-08 12:58:15
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:198954] de Bono, B, 2007-07-08 13:34:15
dbId	198955
displayName	TCR complex interacts with peptide antigen-presenting MHC Class I
eventOf	[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell - Homo sapiens
input	[Complex:R-HSA-198904] Antigen peptide bound class I MHC [plasma membrane] [Complex:R-HSA-198898] T-cell receptor complex with CD8 [plasma membrane]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:198959] How TCRs bind MHCs, peptides, and coreceptors [LiteratureReference:199023] Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3 [LiteratureReference:199027] Crystal structure of a human CD3-epsilon/delta dimer in complex with a UCHT1 single-chain antibody fragment
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	TCR complex interacts with peptide antigen-presenting MHC Class I
orthologousEvent	[Reaction:R-GGA-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Gallus gallus [Reaction:R-SSC-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Sus scrofa [Reaction:R-BTA-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Bos taurus [Reaction:R-CFA-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Canis familiaris [Reaction:R-RNO-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Rattus norvegicus [Reaction:R-MMU-198955] TCR complex interacts with peptide antigen-presenting MHC Class I - Mus musculus
output	[Complex:R-HSA-198897] TCR interacting with antigen-bearing MHC Class I [plasma membrane]
releaseDate	2007-08-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:201344] Trowsdale, J, 2007-08-06 [InstanceEdit:5692843] Barrow, Alexander D, 2015-05-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-198955
summation	[Summation:199611] T cells distinguish foreign material from self through prese...

Referrals

(hasEvent)

[Pathway:R-HSA-198933] Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell