Reactome | DTX recruits beta-arrestin (ARRB) to NOTCH

Schema > Reaction > Entries

DTX recruits beta-arrestin (ARRB) to NOTCH Show undefined attributes

authored	[InstanceEdit:2121208] Egan, SE, Orlic-Milacic, M, 2011-11-14
category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:1980124] Orlic-Milacic, M, 2011-11-08
dbId	1980123
displayName	DTX recruits beta-arrestin (ARRB) to NOTCH
edited	[InstanceEdit:2106576] Orlic-Milacic, M, 2012-02-10 [InstanceEdit:2098673] D'Eustachio, P, 2012-02-06
eventOf	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-1980118] ARRB mediates NOTCH1 ubiquitination - Homo sapiens
inferredFrom	[Reaction:R-DME-2071846] Deltex recruits Kurtz arrestin to Notch - Drosophila melanogaster
input	[DefinedSet:R-HSA-1911410] ARRB [cytosol] [Complex:R-HSA-1852570] NOTCH1:DTX [plasma membrane]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1911367] Regulation of Notch signalling by non-visual beta-arrestin [LiteratureReference:2153461] Synergy between the ESCRT-III complex and Deltex defines a ligand-independent Notch signal
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	DTX recruits beta-arrestin (ARRB) to NOTCH
output	[Complex:R-HSA-1911487] NOTCH1:DTX:ARRB [plasma membrane]
precedingEvent	[Reaction:R-HSA-1980122] DTX binds NOTCH1 - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2121207] Haw, R, 2012-02-06
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1980123
summation	[Summation:2071852] Formation of a complex involving NOTCH, Deltex (DTX) and non...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-1980118] ARRB mediates NOTCH1 ubiquitination
(hasEvent)	[Pathway:R-HSA-2122948] Activated NOTCH1 Transmits Signal to the Nucleus
(inferredTo)	[Reaction:R-DME-2071846] Deltex recruits Kurtz arrestin to Notch

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