Reactome | TIMM9:TIMM10 transfers proteins to TIMM22

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TIMM9:TIMM10 transfers proteins to TIMM22 Show undefined attributes

authored	[InstanceEdit:1955373] May, B, 2011-11-03
category	binding
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:1955370] May, B, 2011-11-03
dbId	1955380
displayName	TIMM9:TIMM10 transfers proteins to TIMM22
edited	[InstanceEdit:1955373] May, B, 2011-11-03
eventOf	[Pathway:R-HSA-1268020] Mitochondrial protein import - Homo sapiens
followingEvent	[Reaction:R-HSA-1307803] TIMM22 inserts proteins into inner membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-1252043] 4xHC-TIMM10B [mitochondrial inner membrane] [EntityWithAccessionedSequence:R-HSA-1252098] TIMM22 [mitochondrial inner membrane] [Complex:R-HSA-1955377] TIMM9:TIMM10:Protein [mitochondrial inner membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1252021] Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria [LiteratureReference:1307738] Multiple pathways for mitochondrial protein traffic [LiteratureReference:1307739] Multiple pathways for sorting mitochondrial precursor proteins
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	TIMM9:TIMM10 transfers proteins to TIMM22
orthologousEvent	[Reaction:R-PFA-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Plasmodium falciparum [Reaction:R-SCE-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Saccharomyces cerevisiae [Reaction:R-SPO-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Schizosaccharomyces pombe [Reaction:R-DDI-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Dictyostelium discoideum [Reaction:R-DME-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Drosophila melanogaster [Reaction:R-GGA-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Gallus gallus [Reaction:R-DRE-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Danio rerio [Reaction:R-SSC-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Sus scrofa [Reaction:R-BTA-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Bos taurus [Reaction:R-CFA-1955380] TIMM9:TIMM10 transfers proteins to TIMM22 - Canis familiaris
output	[Complex:R-HSA-1299470] TIMM9:TIMM10:TIMM10B:TIM22:Protein [mitochondrial inner membrane]
precedingEvent	[Reaction:R-HSA-1299481] TIMM9:TIMM10 binds hydrophobic proteins - Homo sapiens
releaseDate	2012-03-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1914221] D'Eustachio, P, 2011-11-01 [InstanceEdit:2108993] Endo, T, 2012-02-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1955380
summation	[Summation:1955375] TIMM9:TIMM10 with bound substrate protein interacts with FXC...

Referrals

(hasEvent)	[Pathway:R-HSA-1268020] Mitochondrial protein import
(precedingEvent)	[Reaction:R-HSA-1307803] TIMM22 inserts proteins into inner membrane