Reactome | AXIN1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

AXIN1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-1504204] GSK3B:AXIN1 [cytosol] - Homo sapiens
consumedByEvent	[FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex - Homo sapiens [FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding - Homo sapiens [Reaction:R-HSA-195251] Assembly of the destruction complex - Homo sapiens
created	[InstanceEdit:195252] Matthews, L, 2007-04-03 04:36:56
dbId	195249
displayName	AXIN1 [cytosol]
endCoordinate	862
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-195249] Axin1 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-195249] Axin1 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-195249] AXIN1 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-195249] AXIN1 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-195249] AXIN1 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-195249] axin1 [cytosol] - Danio rerio [GenomeEncodedEntity:R-XTR-195249] Ghost homologue of AXIN1 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-195249] AXIN1 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-195249] Axn [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-195249] pry-1 [cytosol] - Caenorhabditis elegans
maxDepth	1
memberOf	[DefinedSet:R-HSA-3640819] AXIN [cytosol] - Homo sapiens
modified	[InstanceEdit:3132750] Wu, G, 2013-02-13
name	AXIN1
producedByEvent	[BlackBoxEvent:R-HSA-8932076] AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 - Homo sapiens [BlackBoxEvent:R-HSA-5251555] Expression of AXIN1 gene - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:O15169] UniProt:O15169 AXIN1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-195249
startCoordinate	1
updateTrackers	[UpdateTracker:9875670] Update Tracker - [EntityWithAccessionedSequence:195249] AXIN1 [cytosol] - v44:[modifyEndCoordinate] [UpdateTracker:9871610] Update Tracker - [EntityWithAccessionedSequence:195249] AXIN1 [cytosol] - v40:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9875670] Update Tracker - [EntityWithAccessionedSequence:195249] AXIN1 [cytosol] - v44:[modifyEndCoordinate] [UpdateTracker:9871610] Update Tracker - [EntityWithAccessionedSequence:195249] AXIN1 [cytosol] - v40:[modifyName]
(normalEntity)	[EntityFunctionalStatus:4839737] decreased_transcript_level and loss_of_function of truncation and missense AXIN mutants [cytosol]
(input)	[FailedReaction:R-HSA-4839746] Truncated AMER1 mutants destabilize the destruction complex [FailedReaction:R-HSA-4791278] APC truncation mutants have impaired AXIN binding [Reaction:R-HSA-195251] Assembly of the destruction complex
(output)	[BlackBoxEvent:R-HSA-8932076] AXIN1 gene expression is inhibited by ESR1 and stimulated by RUNX1 [BlackBoxEvent:R-HSA-5251555] Expression of AXIN1 gene
(hasMember)	[DefinedSet:R-HSA-3640819] AXIN [cytosol]
(hasComponent)	[Complex:R-HSA-1504204] GSK3B:AXIN1 [cytosol] [Complex:R-HSA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

Cite Us!