Reactome | 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)

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3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) Show undefined attributes

authored	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
catalystActivity	[CatalystActivity:193506] long-chain fatty acid-CoA ligase activity of SLC27A2 [endoplasmic reticulum membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:193768] D'Eustachio, P, 2007-02-23 20:48:08
dbId	193743
displayName	3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)
edited	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
eventOf	[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-193753] 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome - Homo sapiens
input	[SimpleEntity:R-ALL-193778] 3,7,24THCA [cytosol] [SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-76194] CoA-SH [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:192044] Human liver-specific very-long-chain acyl-coenzyme A synthetase: cDNA cloning and characterization of a second enzymatically active protein [LiteratureReference:191995] The human liver-specific homolog of very long-chain acyl-CoA synthetase is cholate:CoA ligase [LiteratureReference:193432] Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) 3,7,24THCA + ATP + CoASH => 3,7,24THCA-CoA + AMP + pyrophosphate + H2O (SLC27A2 "VLCS")
orthologousEvent	[Reaction:R-CEL-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Caenorhabditis elegans [Reaction:R-DME-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Drosophila melanogaster [Reaction:R-GGA-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Gallus gallus [Reaction:R-XTR-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Xenopus tropicalis [Reaction:R-SSC-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Sus scrofa [Reaction:R-BTA-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Bos taurus [Reaction:R-CFA-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Canis familiaris [Reaction:R-RNO-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Rattus norvegicus [Reaction:R-MMU-193743] 3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) - Mus musculus
output	[SimpleEntity:R-ALL-193739] 3,7,24THCA-CoA [cytosol] [SimpleEntity:R-ALL-76577] AMP [cytosol] [SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-111294] PPi [cytosol]
precedingEvent	[BlackBoxEvent:R-HSA-193786] 3,7,24THCA is translocated from the mitochondrial matrix to the cytosol - Homo sapiens
releaseDate	2007-05-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-193743
summation	[Summation:193754] 3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...

Referrals

(hasEvent)	[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol
(precedingEvent)	[BlackBoxEvent:R-HSA-193753] 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome