3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...

created [InstanceEdit:193768] D'Eustachio, P, 2007-02-23 20:48:08
dbId 193754
displayName 3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-chole...
literatureReference
modified [InstanceEdit:194078] D'Eustachio, P, 2007-03-08 15:03:08
schemaClass Summation
text 3,7,24THCA (25(R) 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate), coenzyme A, and ATP react to form the CoA conjugate of 3,7,24THCA, AMP, pyrophosphate and water. This cytosolic reaction is catalyzed by SLC27A2 (VLCS). SLC27A5 (BACS) also catalyzes this reaction; the relative contributions of the two enzymes to de novo bile acid synthesis in vivo are not certain (Mihalik et al. 2002).
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