Reactome | Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA

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Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA Show undefined attributes

authored	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
catalystActivity	[CatalystActivity:191973] alpha-methylacyl-CoA racemase activity of AMACR [peroxisomal matrix]
category	transition
compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:193768] D'Eustachio, P, 2007-02-23 20:48:08
dbId	193736
displayName	Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
edited	[InstanceEdit:193783] D'Eustachio, P, 2007-02-23 20:35:09
eventOf	[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol - Homo sapiens
followingEvent	[Reaction:R-HSA-193508] (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-193732] 3,7,24THCA-CoA [peroxisomal matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:192112] Purification and characterization of an alpha-methylacyl-CoA racemase from human liver [LiteratureReference:192185] Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans [LiteratureReference:193502] Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA 3,7,24THCA-CoA => (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA
orthologousEvent	[Reaction:R-CEL-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Caenorhabditis elegans [Reaction:R-DME-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Drosophila melanogaster [Reaction:R-GGA-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Gallus gallus [Reaction:R-XTR-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Xenopus tropicalis [Reaction:R-DRE-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Danio rerio [Reaction:R-BTA-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Bos taurus [Reaction:R-RNO-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Rattus norvegicus [Reaction:R-MMU-193736] Isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA - Mus musculus
output	[SimpleEntity:R-ALL-193732] 3,7,24THCA-CoA [peroxisomal matrix]
precedingEvent	[Reaction:R-HSA-193753] 3,7,24THCA-CoA is translocated from the cytosol to the peroxisome - Homo sapiens
releaseDate	2007-05-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:197117] D'Eustachio, P, 2007-04-30 14:43:26
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-193736
summation	[Summation:193750] The isomerization of 3,7,24THCA-CoA to (24R, 25R) 3alpha,7a...

Referrals

(hasEvent)	[Pathway:R-HSA-193775] Synthesis of bile acids and bile salts via 24-hydroxycholesterol
(precedingEvent)	[Reaction:R-HSA-193508] (24R, 25R) 3alpha,7alpha,24-trihydroxy-5beta-cholestanoyl-CoA is oxidized to 3alpha,7alpha-dihydroxy-5beta-cholest-24-one-CoA