Reactome | Ub-NOTCH1:NUMB:ITCH [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:1911543] Orlic-Milacic, M, 2011-11-01
dbId	1911544
displayName	Ub-NOTCH1:NUMB:ITCH [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-HSA-975995] ITCH [cytosol] [EntityWithAccessionedSequence:R-HSA-443595] NUMB [plasma membrane] [Complex:R-HSA-1911534] Ub-NOTCH1 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
isChimeric	false
maxDepth	4
modified	[InstanceEdit:2213009] Matthews, L, 2012-04-27
name	Ub-NOTCH1:NUMB:ITCH
producedByEvent	[Reaction:R-HSA-1912386] Ubiquitination of NOTCH1 by ITCH in the absence of ligand - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-1911544
updateTrackers	[UpdateTracker:9872672] Update Tracker - [Complex:1911544] Ub-NOTCH1:NUMB:ITCH [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9875546] Update Tracker - [Complex:1911544] Ub-NOTCH1:NUMB:ITCH [plasma membrane] - v44:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9872672] Update Tracker - [Complex:1911544] Ub-NOTCH1:NUMB:ITCH [plasma membrane] - v41:[updateContainedComponent] [UpdateTracker:9875546] Update Tracker - [Complex:1911544] Ub-NOTCH1:NUMB:ITCH [plasma membrane] - v44:[updateContainedComponent]
(output)	[Reaction:R-HSA-1912386] Ubiquitination of NOTCH1 by ITCH in the absence of ligand