Reactome | FGFR2c binds to FGF

Schema > BlackBoxEvent > Entries

FGFR2c binds to FGF Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
category	omitted
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:190259] de Bono, B, 2006-12-18 16:03:25
dbId	190258
displayName	FGFR2c binds to FGF
eventOf	[Pathway:R-HSA-190375] FGFR2c ligand binding and activation - Homo sapiens
followingEvent	[Reaction:R-HSA-190413] Autocatalytic phosphorylation of FGFR2c - Homo sapiens
input	2 × [DefinedSet:R-HSA-192596] FGFR2c [plasma membrane] 2 × [DefinedSet:R-HSA-189957] FGFR2c-binding FGFs [extracellular region] [SimpleEntity:R-ALL-190915] HS [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. [LiteratureReference:191519] Structural basis for fibroblast growth factor receptor activation
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	FGFR2c binds to FGF
orthologousEvent	[BlackBoxEvent:R-CEL-190258] FGFR2c binds to FGF - Caenorhabditis elegans [BlackBoxEvent:R-DME-190258] FGFR2c binds to FGF - Drosophila melanogaster [BlackBoxEvent:R-GGA-190258] FGFR2c binds to FGF - Gallus gallus [BlackBoxEvent:R-XTR-190258] FGFR2c binds to FGF - Xenopus tropicalis [BlackBoxEvent:R-DRE-190258] FGFR2c binds to FGF - Danio rerio [BlackBoxEvent:R-BTA-190258] FGFR2c binds to FGF - Bos taurus [BlackBoxEvent:R-CFA-190258] FGFR2c binds to FGF - Canis familiaris [BlackBoxEvent:R-RNO-190258] FGFR2c binds to FGF - Rattus norvegicus [BlackBoxEvent:R-MMU-190258] FGFR2c binds to FGF - Mus musculus
output	[DefinedSet:R-HSA-192594] FGFR2c homodimer bound to FGF [plasma membrane]
regulatedBy	[Requirement:R-HSA-190313] Requirement by 'HS [extracellular region]'
releaseDate	2007-02-28
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-190258
summation	[Summation:192608] In this reaction, FGF receptor 2c in the plasma membrane bin...
updateTrackers	[UpdateTracker:9789682] Update Tracker - [BlackBoxEvent:190258] FGFR2c binds to FGF - v37:[addLiteratureReference, add_removeInput, removeRegulator] [UpdateTracker:9789035] Update Tracker - [BlackBoxEvent:190258] FGFR2c binds to FGF - v39:[add_removeRegulator]

Referrals

(updatedInstance)	[UpdateTracker:9789682] Update Tracker - [BlackBoxEvent:190258] FGFR2c binds to FGF - v37:[addLiteratureReference, add_removeInput, removeRegulator] [UpdateTracker:9789035] Update Tracker - [BlackBoxEvent:190258] FGFR2c binds to FGF - v39:[add_removeRegulator]
(hasEvent)	[Pathway:R-HSA-190375] FGFR2c ligand binding and activation
(precedingEvent)	[Reaction:R-HSA-190413] Autocatalytic phosphorylation of FGFR2c