Reactome | FGFR2c binds to FGF

Schema > BlackBoxEvent > Entries

FGFR2c binds to FGF Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10926269
displayName	FGFR2c binds to FGF
eventOf	[Pathway:R-CEL-190375] FGFR2c ligand binding and activation - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-190413] Autocatalytic phosphorylation of FGFR2c - Caenorhabditis elegans
inferredFrom	[BlackBoxEvent:R-HSA-190258] FGFR2c binds to FGF - Homo sapiens
input	2 × [DefinedSet:R-CEL-189953] FGFR1c-binding FGFs [extracellular region] 2 × [DefinedSet:R-CEL-192596] FGFR2c [plasma membrane] [SimpleEntity:R-ALL-190915] HS [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	FGFR2c binds to FGF
output	[DefinedSet:R-CEL-192594] FGFR2c homodimer bound to FGF [plasma membrane]
regulatedBy	[Requirement:R-HSA-190314] Requirement by 'HS [extracellular region]'
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-190258
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-190375] FGFR2c ligand binding and activation
(precedingEvent)	[Reaction:R-CEL-190413] Autocatalytic phosphorylation of FGFR2c
(inferredTo)	[BlackBoxEvent:R-HSA-190258] FGFR2c binds to FGF