Reactome | FGFR1b binds to FGF

Schema > Reaction > Entries

FGFR1b binds to FGF Show undefined attributes

authored	[InstanceEdit:190908] de Bono, B, 2007-01-10 10:27:18
category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:190250] de Bono, B, 2006-12-18 15:42:29
dbId	190245
displayName	FGFR1b binds to FGF
eventOf	[Pathway:R-HSA-190370] FGFR1b ligand binding and activation - Homo sapiens
followingEvent	[Reaction:R-HSA-190427] Autocatalytic phosphorylation of FGFR1b - Homo sapiens
input	2 × [EntityWithAccessionedSequence:R-HSA-189878] FGFR1b [plasma membrane] 2 × [DefinedSet:R-HSA-189963] FGFR1b-binding FGFs [extracellular region] [SimpleEntity:R-ALL-190915] HS [extracellular region]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:190251] Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family.
modified	[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name	FGFR1b binds to FGF
orthologousEvent	[Reaction:R-CEL-190245] FGFR1b binds to FGF - Caenorhabditis elegans [Reaction:R-DME-190245] FGFR1b binds to FGF - Drosophila melanogaster [Reaction:R-GGA-190245] FGFR1b binds to FGF - Gallus gallus [Reaction:R-XTR-190245] FGFR1b binds to FGF - Xenopus tropicalis [Reaction:R-DRE-190245] FGFR1b binds to FGF - Danio rerio [Reaction:R-SSC-190245] FGFR1b binds to FGF - Sus scrofa [Reaction:R-BTA-190245] FGFR1b binds to FGF - Bos taurus [Reaction:R-CFA-190245] FGFR1b binds to FGF - Canis familiaris [Reaction:R-RNO-190245] FGFR1b binds to FGF - Rattus norvegicus [Reaction:R-MMU-190245] FGFR1b binds to FGF - Mus musculus
output	[Complex:R-HSA-190226] FGFR1b homodimer bound to FGF [plasma membrane]
precedingEvent	[BlackBoxEvent:R-HSA-480515] Expression of FGF2 - Homo sapiens
previousReviewStatus	[ReviewStatus:9821384] two stars
regulatedBy	[Requirement:R-HSA-190317] Requirement by 'HS [extracellular region]' [PositiveRegulation:9839338] Positive regulation by 'FGF2:TGFBR3:GIPC1'
regulationReference	[RegulationReference:9840936] Positive regulation by 'FGF2:TGFBR3:GIPC1' Binding of two growth factor families to separate domains of the proteoglycan betaglycan
releaseDate	2007-02-28
reviewStatus	[ReviewStatus:9821385] four stars
reviewed	[InstanceEdit:192607] Mohammadi, M, 2007-02-06 21:44:35
revised	[InstanceEdit:1493881] Rothfels, K, 2011-08-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-190245
summation	[Summation:192407] In this reaction, FGF receptor in the plasma membrane binds ...

Referrals

(hasEvent)	[Pathway:R-HSA-190370] FGFR1b ligand binding and activation
(precedingEvent)	[Reaction:R-HSA-190427] Autocatalytic phosphorylation of FGFR1b