Reactome | TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol]

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TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-1839015] TRIM24-p-FGFR1 fusion mutant dimer [cytosol] - Homo sapiens [Complex:R-HSA-1839015] TRIM24-p-FGFR1 fusion mutant dimer [cytosol] - Homo sapiens
created	[InstanceEdit:1839013] Rothfels, K, 2011-10-27
crossReference	[DatabaseIdentifier:12020830] Mondo:0002582
dbId	1839012
disease	[Disease:1604519] subacute leukemia [Disease:1614677] myelodysplastic myeloproliferative cancer [Disease:2317476] acute lymphocytic leukemia
displayName	TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol]
endCoordinate	626
hasModifiedResidue	[FragmentInsertionModification:1614443] Insertion of residues 429 to 822 at 627 from UniProt:P11362 FGFR1 [ModifiedResidue:1838976] O4'-phospho-L-tyrosine at 766 [ModifiedResidue:1838977] O4'-phospho-L-tyrosine at unknown position
inDisease	true
literatureReference	[LiteratureReference:1606519] 8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes
maxDepth	1
modified	[InstanceEdit:9832769] Orlic-Milacic, Marija, 2023-04-07
name	TRIM24(1-626)-p-FGFR1(429-822) fusion TRIM24-p-2Y-FGFR1 fusion t(7;8) TRIM24-p-FGFR1 fusion
referenceEntity	[ReferenceGeneProduct:uniprot:O15164] UniProt:O15164 TRIM24
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1839012
startCoordinate	1
updateTrackers	[UpdateTracker:9902920] Update Tracker - [EntityWithAccessionedSequence:1839012] TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] - v79:[modifyName] [UpdateTracker:9905742] Update Tracker - [EntityWithAccessionedSequence:1839012] TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] - v85:[add_removeDisease] [UpdateTracker:9874443] Update Tracker - [EntityWithAccessionedSequence:1839012] TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] - v43:[modifyName] [UpdateTracker:9890744] Update Tracker - [EntityWithAccessionedSequence:1839012] TRIM24(1-626)-p-FGFR1(429-822) fusion [cytosol] - v52:[modifyName]

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[Complex:R-HSA-1839015] TRIM24-p-FGFR1 fusion mutant dimer [cytosol]