Reactome | EPS15 [cytosol]

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EPS15 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-182947] EPS15:HGS:STAM [cytosol] - Homo sapiens [Complex:R-HSA-8871145] PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] - Homo sapiens [Complex:R-HSA-8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] - Homo sapiens [Complex:R-HSA-8868632] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] - Homo sapiens [Complex:R-HSA-8856806] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8862280] FCHo proteins bind nascent clathrin-coated pit - Homo sapiens
created	[InstanceEdit:182919] Jassal, B, 2006-07-21 10:17:37
dbId	182920
displayName	EPS15 [cytosol]
endCoordinate	896
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-182920] EPS15 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-182920] Eps15 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-182920] EPS15 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-182920] EPS15 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-182920] EPS15 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-182920] eps15 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-182920] eps15 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-182920] EPS15 [cytosol] - Gallus gallus [EntityWithAccessionedSequence:R-DME-182920] Eps-15 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-182920] ehs-1 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-182920] eps15 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-PFA-182920] EPS15 [cytosol] - Plasmodium falciparum [EntityWithAccessionedSequence:R-PFA-182920-2] EPS15 [cytosol] - Plasmodium falciparum [DefinedSet:R-PFA-182920-3] Homologues of EPS15 [cytosol] - Plasmodium falciparum
maxDepth	1
memberOf	[DefinedSet:R-HSA-8866243] EPS15,EPN1,EPN2 [cytosol] - Homo sapiens
modified	[InstanceEdit:8876264] Orlic-Milacic, Marija, 2016-06-10
name	EPS15 Eps15
positivelyRegulates	[PositiveRegulation:9934674] Positive regulation by 'EPS15 [cytosol]'
producedByEvent	[BlackBoxEvent:R-HSA-8869438] Dissociation of clathrin-associated proteins - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:P42566] UniProt:P42566 EPS15
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-182920
startCoordinate	1
updateTrackers	[UpdateTracker:9884989] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v45:[addName] [UpdateTracker:9878638] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v44:[modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9884989] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v45:[addName] [UpdateTracker:9878638] Update Tracker - [EntityWithAccessionedSequence:182920] EPS15 [cytosol] - v44:[modifyEndCoordinate]
(output)	[BlackBoxEvent:R-HSA-8869438] Dissociation of clathrin-associated proteins
(hasComponent)	[Complex:R-HSA-8871145] PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] [Complex:R-HSA-8868620] PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] [Complex:R-HSA-8868627] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] [Complex:R-HSA-8868626] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] [Complex:R-HSA-8868624] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] [Complex:R-HSA-8868629] PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] [Complex:R-HSA-8868632] PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] [Complex:R-HSA-8862276] PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] [Complex:R-HSA-8856806] PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] [Complex:R-HSA-182947] EPS15:HGS:STAM [cytosol]
(input)	[Reaction:R-HSA-8862280] FCHo proteins bind nascent clathrin-coated pit
(hasMember)	[DefinedSet:R-HSA-8866243] EPS15,EPN1,EPN2 [cytosol]
(regulator)	[PositiveRegulation:9934674] Positive regulation by 'EPS15 [cytosol]'

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