Reactome | DARPP-32 phosphorylated on T34 [cytosol]

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DARPP-32 phosphorylated on T34 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-180025] Phosphorylated (T34) DARPP-32:PP1A [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-201787] PPP3 complex dephosphorylates DARPP-32 on Thr34 - Homo sapiens [Reaction:R-HSA-180038] DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function - Homo sapiens
created	[InstanceEdit:180049] Jassal, B, 2006-05-16 12:25:23
dbId	180075
displayName	DARPP-32 phosphorylated on T34 [cytosol]
hasMember	[EntityWithAccessionedSequence:R-HSA-177274] p-T34-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180065] p-T34,S102-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180062] p-T34,S102,S137-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180036] p-T34,S137-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180045] p-T34,T75-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180033] p-T34,T75,S102-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180057] p-T34,T75,S102,S137-PPP1R1B [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-180023] p-T34,T75,S137-PPP1R1B [cytosol] - Homo sapiens
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-177274] phospho-Ppp1r1b [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-177274] phospho-Ppp1r1b [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-177274] phospho-PPP1R1B [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-177274] phospho-PPP1R1B [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-177274] phospho-PPP1R1B [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-177274] phospho-ppp1r1b [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-177274] phospho-ppp1r1b [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-177274] phospho-PPP1R1B [cytosol] - Gallus gallus
maxDepth	2
modified	[InstanceEdit:9012335] D'Eustachio, Peter, 2017-07-12
name	DARPP-32 phosphorylated on T34
producedByEvent	[Reaction:R-HSA-177275] PKA phosphorylates DARPP-32 on Thr34 - Homo sapiens
schemaClass	DefinedSet
species	[Species:48887] Homo sapiens
stId	R-HSA-180075
updateTrackers	[UpdateTracker:9897338] Update Tracker - [DefinedSet:180075] DARPP-32 phosphorylated on T34 [cytosol] - v62:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9897338] Update Tracker - [DefinedSet:180075] DARPP-32 phosphorylated on T34 [cytosol] - v62:[modifyName]
(input)	[Reaction:R-HSA-201787] PPP3 complex dephosphorylates DARPP-32 on Thr34 [Reaction:R-HSA-180038] DARPP-32 phosphorylated on T34 binds to PP1, inhibiting its function
(output)	[Reaction:R-HSA-177275] PKA phosphorylates DARPP-32 on Thr34
(hasComponent)	[Complex:R-HSA-180025] Phosphorylated (T34) DARPP-32:PP1A [cytosol]
(activeUnit)	[CatalystActivity:180074] protein phosphatase regulator activity of Phosphorylated (T34) DARPP-32:PP1A [cytosol]

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