Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins

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APC/C:Cdc20 mediated degradation of mitotic proteins Show undefined attributes

created	[InstanceEdit:176411] Matthews, L, 2006-03-07 23:42:05
crossReference	[DatabaseIdentifier:12819491] BioModels Database:BIOMD0000000186 [DatabaseIdentifier:12819455] BioModels Database:BIOMD0000000293 [DatabaseIdentifier:12819489] BioModels Database:BIOMD0000000939 [DatabaseIdentifier:12819457] BioModels Database:BIOMD0000000220 [DatabaseIdentifier:12819639] BioModels Database:BIOMD0000000194 [DatabaseIdentifier:12819641] BioModels Database:BIOMD0000000193 [DatabaseIdentifier:12819493] BioModels Database:BIOMD0000000187 [DatabaseIdentifier:12819587] BioModels Database:BIOMD0000000723
dbId	176409
displayName	APC/C:Cdc20 mediated degradation of mitotic proteins
eventOf	[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Homo sapiens
figure	[Figure:177059] /figures/Cdc20.targets.jpg
goBiologicalProcess	[GO_BiologicalProcess:18638] regulation of exit from mitosis
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-179419] APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint - Homo sapiens [Reaction:R-HSA-174238] Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 - Homo sapiens [Pathway:R-HSA-174048] APC/C:Cdc20 mediated degradation of Cyclin B - Homo sapiens [Pathway:R-HSA-174154] APC/C:Cdc20 mediated degradation of Securin - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2022-04-07
literatureReference	[LiteratureReference:177002] The D box asserts itself [LiteratureReference:69012] Whose end is destruction: cell division and the anaphase-promoting complex
maxDepth	4
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	APC/C:Cdc20 mediated degradation of mitotic proteins
orthologousEvent	[Pathway:R-SPO-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Schizosaccharomyces pombe [Pathway:R-DDI-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Dictyostelium discoideum [Pathway:R-DME-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Drosophila melanogaster [Pathway:R-GGA-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Gallus gallus [Pathway:R-XTR-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Xenopus tropicalis [Pathway:R-DRE-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Danio rerio [Pathway:R-SSC-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Sus scrofa [Pathway:R-BTA-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Bos taurus [Pathway:R-CFA-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Canis familiaris [Pathway:R-RNO-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Rattus norvegicus [Pathway:R-MMU-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Mus musculus
releaseDate	2006-04-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:177300] Peters, JM, 2006-03-27 22:55:09
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-176409
summation	[Summation:177042] Following phosphorylation of the APC/C core subunits by mito...
updateTrackers	[UpdateTracker:9781193] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v61:[updateIndirectRLE] [UpdateTracker:9785874] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v51:[addHasEvent] [UpdateTracker:9774960] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v80:[updateIndirectRLE] [UpdateTracker:9787686] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v44:[updateIndirectRLE] [UpdateTracker:9789409] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v38:[addLiteratureReference, updateContainedPathway]

Referrals

(updatedInstance)

[UpdateTracker:9781193] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v61:[updateIndirectRLE]
[UpdateTracker:9785874] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v51:[addHasEvent]
[UpdateTracker:9774960] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v80:[updateIndirectRLE]
[UpdateTracker:9787686] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v44:[updateIndirectRLE]
[UpdateTracker:9789409] Update Tracker - [Pathway:176409] APC/C:Cdc20 mediated degradation of mitotic proteins - v38:[addLiteratureReference, updateContainedPathway]

(hasEvent)

[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

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