Reactome | APC/C:Cdc20 mediated degradation of mitotic proteins

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APC/C:Cdc20 mediated degradation of mitotic proteins Show undefined attributes

created	[InstanceEdit:10651445] Weiser, Joel, 2026-03-16
dbId	10729252
displayName	APC/C:Cdc20 mediated degradation of mitotic proteins
eventOf	[Pathway:R-XTR-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Xenopus tropicalis
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:18638] regulation of exit from mitosis
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-XTR-179419] APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint - Xenopus tropicalis [Reaction:R-XTR-174238] Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 - Xenopus tropicalis [Pathway:R-XTR-174048] APC/C:Cdc20 mediated degradation of Cyclin B - Xenopus tropicalis [Pathway:R-XTR-174154] APC/C:Cdc20 mediated degradation of Securin - Xenopus tropicalis
inferredFrom	[Pathway:R-HSA-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	APC/C:Cdc20 mediated degradation of mitotic proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:205621] Xenopus tropicalis
stId	R-XTR-176409
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-XTR-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
(inferredTo)	[Pathway:R-HSA-176409] APC/C:Cdc20 mediated degradation of mitotic proteins

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