Reactome | Recruitment of the Rad9-Hus1-Rad1 complex to DNA

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Recruitment of the Rad9-Hus1-Rad1 complex to DNA Show undefined attributes

authored	[InstanceEdit:176227] Borowiec, JA, 2006-02-25 17:40:15
catalystActivity	[CatalystActivity:176122] DNA clamp loader activity of Rad17-RFC complex bound to DNA [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:176246] D'Eustachio, P, 2006-03-03 16:44:08
dbId	176264
displayName	Recruitment of the Rad9-Hus1-Rad1 complex to DNA
edited	[InstanceEdit:176160] D'Eustachio, P, 2006-02-25 17:41:28
eventOf	[Pathway:R-HSA-176187] Activation of ATR in response to replication stress - Homo sapiens
followingEvent	[Reaction:R-HSA-176116] Recruitment and activation of Chk1 - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:7962] DNA replication
input	[Complex:R-HSA-176204] Rad17-RFC complex bound to DNA [nucleoplasm] [Complex:R-HSA-176312] RAD9:HUS1:RAD1 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:176370] Replication protein A-mediated recruitment and activation of Rad17 complexes [LiteratureReference:176117] Biochemical characterization of DNA damage checkpoint complexes: clamp loader and clamp complexes with specificity for 5' recessed DNA [LiteratureReference:176209] Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro [LiteratureReference:176164] A human homolog of the Schizosaccharomyces pombe rad9+ checkpoint control gene [LiteratureReference:176110] Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue [LiteratureReference:176356] Physical interactions among human checkpoint control proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Recruitment of the Rad9-Hus1-Rad1 complex to DNA Recruitment of the 9-1-1 complex to DNA
orthologousEvent	[Reaction:R-SCE-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Saccharomyces cerevisiae [Reaction:R-SPO-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Schizosaccharomyces pombe [Reaction:R-CEL-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Caenorhabditis elegans [Reaction:R-DME-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Drosophila melanogaster [Reaction:R-GGA-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Gallus gallus [Reaction:R-XTR-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Xenopus tropicalis [Reaction:R-DRE-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Danio rerio [Reaction:R-SSC-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Sus scrofa [Reaction:R-BTA-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Bos taurus [Reaction:R-CFA-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Canis familiaris [Reaction:R-RNO-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Rattus norvegicus [Reaction:R-MMU-176264] Recruitment of the Rad9-Hus1-Rad1 complex to DNA - Mus musculus
output	[Complex:R-HSA-176256] Rad9-Hus1-Rad1 bound to DNA [nucleoplasm]
precedingEvent	[Reaction:R-HSA-176101] Recruitment of Rad17-RFC complex to DNA - Homo sapiens
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-176264
summation	[Summation:176381] The 9-1-1 complex is a heterotrimeric ring-shaped structure ...

Referrals

(hasEvent)	[Pathway:R-HSA-176187] Activation of ATR in response to replication stress
(precedingEvent)	[Reaction:R-HSA-176116] Recruitment and activation of Chk1

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