Reactome | Target DNA binding

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Target DNA binding Show undefined attributes

authored	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:175576] Gopinathrao, G, 2006-02-23 23:50:37
crossReference	[DatabaseIdentifier:12020765] Mondo:0005109
dbId	175108
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Target DNA binding
edited	[InstanceEdit:180401] Gopinathrao, G, D'Eustachio, P, 2006-05-18 20:10:22
eventOf	[Pathway:R-HSA-175567] Integration of viral DNA into host genomic DNA - Homo sapiens
figure	[Figure:188489] /figures/integ_cleavage.jpg
followingEvent	[Reaction:R-HSA-164523] Transesterification to connect viral DNA 3' ends to host DNA 5' ends - Homo sapiens
input	[GenomeEncodedEntity:R-HSA-175158] Host genomic DNA [nucleoplasm] [Complex:R-HSA-175416] IN bound to sticky 3' ends of viral DNA in PIC [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[Book:175927] 9780879695712 Integration Retroviruses Coffin, JM [LiteratureReference:177403] Retroviral DNA integration--mechanism and consequences [LiteratureReference:177396] Genome-wide analysis of retroviral DNA integration
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Target DNA binding
output	[Complex:R-HSA-175224] IN:viral DNA bound to host genomic DNA with staggered ends [nucleoplasm] [Complex:R-HSA-177527] viral PIC proteins [nucleoplasm]
precedingEvent	[Reaction:R-HSA-162590] Import of PIC to the Host Nucleus - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:188934] Bushman, FD, 2006-10-30 22:19:13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-175108
summation	[Summation:180098] How the PIC finds favored sites on target DNA has not been f...

Referrals

(precedingEvent)	[Reaction:R-HSA-164523] Transesterification to connect viral DNA 3' ends to host DNA 5' ends
(hasEvent)	[Pathway:R-HSA-175567] Integration of viral DNA into host genomic DNA

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