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Schema
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Pathway
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Entries
Regulation of Glucokinase by Glucokinase Regulatory Protein
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created
[InstanceEdit:170815] D'Eustachio, P, 2006-01-17 15:36:38
dbId
170822
displayName
Regulation of Glucokinase by Glucokinase Regulatory Protein
edited
[InstanceEdit:174827] D'Eustachio, P, 2006-02-20 18:39:56
eventOf
[Pathway:R-HSA-70171] Glycolysis - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:15773] regulation of glycolytic process
hasDiagram
false
hasEHLD
false
hasEvent
[Reaction:R-HSA-170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex - Homo sapiens
[Reaction:R-HSA-170799] cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) - Homo sapiens
[Reaction:R-HSA-170796] NPC transports GCK1:GKRP from cytosol to nucleoplasm - Homo sapiens
[Reaction:R-HSA-170810] nucleoplasmic GCK1:GKRP complex => glucokinase (GCK1) + glucokinase regulatory protein (GKRP) - Homo sapiens
[Reaction:R-HSA-170825] glucokinase [nucleoplasm] => glucokinase [cytosol] - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:170817] Differences in regulatory properties between human and rat glucokinase regulatory protein
[LiteratureReference:170794] Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
modified
[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name
Regulation of Glucokinase by Glucokinase Regulatory Protein
orthologousEvent
[Pathway:R-PFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Plasmodium falciparum
[Pathway:R-SCE-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Saccharomyces cerevisiae
[Pathway:R-SPO-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Schizosaccharomyces pombe
[Pathway:R-CEL-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Caenorhabditis elegans
[Pathway:R-DME-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Drosophila melanogaster
[Pathway:R-GGA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Gallus gallus
[Pathway:R-XTR-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Xenopus tropicalis
[Pathway:R-BTA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Bos taurus
[Pathway:R-CFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Canis familiaris
[Pathway:R-RNO-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Rattus norvegicus
[Pathway:R-MMU-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Mus musculus
releaseDate
2005-06-13
reviewStatus
[ReviewStatus:9821382] five stars
revised
[InstanceEdit:450087] D'Eustachio, P, 2009-12-11
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-170822
summation
[Summation:170826] Glucokinase (GCK1) is negatively regulated by glucokinase re...
Referrals
(hasEvent)
[Pathway:R-HSA-70171] Glycolysis
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