Reactome | Regulation of Glucokinase by Glucokinase Regulatory Protein

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Regulation of Glucokinase by Glucokinase Regulatory Protein Show undefined attributes

created	[InstanceEdit:170815] D'Eustachio, P, 2006-01-17 15:36:38
dbId	170822
displayName	Regulation of Glucokinase by Glucokinase Regulatory Protein
doi	10.3180/R-HSA-170822.6
edited	[InstanceEdit:174827] D'Eustachio, P, 2006-02-20 18:39:56
eventOf	[Pathway:R-HSA-70171] Glycolysis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:15773] regulation of glycolytic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-170824] glucokinase (GCK1) + glucokinase regulatory protein (GKRP) <=> GCK1:GKRP complex - Homo sapiens [Reaction:R-HSA-170799] cytosolic GCK1:GKRP complex <=> glucokinase (GCK1) + glucokinase regulatory protein (GKRP) - Homo sapiens [BlackBoxEvent:R-HSA-170796] NPC transports GCK1:GCKR from cytosol to nucleoplasm - Homo sapiens [Reaction:R-HSA-170810] nucleoplasmic GCK1:GCKR complex => glucokinase (GCK1) + glucokinase regulatory protein (GCKR) - Homo sapiens [BlackBoxEvent:R-HSA-170825] NPC exports GCK1 from nucleus - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2010-03-16
literatureReference	[LiteratureReference:170817] Differences in regulatory properties between human and rat glucokinase regulatory protein [LiteratureReference:170794] Nuclear import of hepatic glucokinase depends upon glucokinase regulatory protein, whereas export is due to a nuclear export signal sequence in glucokinase
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Regulation of Glucokinase by Glucokinase Regulatory Protein
orthologousEvent	[Pathway:R-DRE-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Danio rerio [Pathway:R-PFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Plasmodium falciparum [Pathway:R-SCE-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Saccharomyces cerevisiae [Pathway:R-SPO-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Schizosaccharomyces pombe [Pathway:R-CEL-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Caenorhabditis elegans [Pathway:R-DME-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Drosophila melanogaster [Pathway:R-GGA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Gallus gallus [Pathway:R-XTR-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Xenopus tropicalis [Pathway:R-BTA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Bos taurus [Pathway:R-CFA-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Canis familiaris [Pathway:R-RNO-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Rattus norvegicus [Pathway:R-MMU-170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - Mus musculus
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:450087] D'Eustachio, P, 2009-12-11
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-170822
summation	[Summation:170826] Glucokinase (GCK1) is negatively regulated by glucokinase re...
updateTrackers	[UpdateTracker:9790968] Update Tracker - [Pathway:170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - v32:[modifyText, updateContainedRLE] [UpdateTracker:9792250] Update Tracker - [Pathway:170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - v22:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9790968] Update Tracker - [Pathway:170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - v32:[modifyText, updateContainedRLE] [UpdateTracker:9792250] Update Tracker - [Pathway:170822] Regulation of Glucokinase by Glucokinase Regulatory Protein - v22:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-70171] Glycolysis

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