Translocation of Cdc25 to the nucleus

Stable Identifier
Reaction [transition]
Homo sapiens
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The localization of the Cdc25A, B and C proteins is dynamic involving the shuttling of these proteins between the nucleus and the cytoplasm. Sequences in these proteins mediate both nuclear export and import (Kallstrom et al., 2005; Lindqvist et al., 2004; Graves et al, 2001; Takizawa and Morgan, 2000).

Literature References
PubMed ID Title Journal Year
15572030 Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import

Pospisil, V, Kallstrom, H, Rosenthal, CK, Lindqvist, A, Lundgren, A

Exp Cell Res 2005
11313932 Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

Piwnica-Worms, H, Lovly, CM, Uy, GL, Graves, PR

Oncogene 2001
15456846 Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress

Kallstrom, H, Karlsson Rosenthal, C, Lindqvist, A

J Cell Sci 2004
Orthologous Events
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