Translocation of Cdc25 to the nucleus

Stable Identifier
R-HSA-170159
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

The localization of the Cdc25A, B and C proteins is dynamic involving the shuttling of these proteins between the nucleus and the cytoplasm. Sequences in these proteins mediate both nuclear export and import (Kallstrom et al., 2005; Lindqvist et al., 2004; Graves et al, 2001; Takizawa and Morgan, 2000).

Literature References
PubMed ID Title Journal Year
11313932 Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding.

Graves, PR, Lovly, CM, Uy, GL, Piwnica-Worms, H

Oncogene 2001
15572030 Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import

Kallstrom, H, Lindqvist, A, Pospisil, V, Lundgren, A, Rosenthal, CK

Exp Cell Res 2005
15456846 Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress

Lindqvist, A, Kallstrom, H, Karlsson Rosenthal, C

J Cell Sci 2004
Participants
Participant Of
Orthologous Events
Created