Reactome | Translocation of Cdc25 to the nucleus

Translocation of Cdc25 to the nucleus

Stable Identifier

R-HSA-170159

Type

Reaction [transition]

Species

Homo sapiens

Compartment

nuclear envelope

ReviewStatus

5/5

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The localization of the Cdc25A, B and C proteins is dynamic involving the shuttling of these proteins between the nucleus and the cytoplasm. Sequences in these proteins mediate both nuclear export and import (Kallstrom et al., 2005; Lindqvist et al., 2004; Graves et al, 2001; Takizawa and Morgan, 2000).

Literature References

PubMed ID	Title	Journal	Year
15572030	Cdc25A localisation and shuttling: characterisation of sequences mediating nuclear export and import Pospisil, V, Kallstrom, H, Rosenthal, CK, Lindqvist, A, Lundgren, A	Exp Cell Res	2005
11313932	Localization of human Cdc25C is regulated both by nuclear export and 14-3-3 protein binding. Piwnica-Worms, H, Lovly, CM, Uy, GL, Graves, PR	Oncogene	2001
15456846	Characterisation of Cdc25B localisation and nuclear export during the cell cycle and in response to stress Kallstrom, H, Karlsson Rosenthal, C, Lindqvist, A	J Cell Sci	2004