Reactome | Priming and Initiation of Transcription

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Priming and Initiation of Transcription Show undefined attributes

authored	[InstanceEdit:193029] Bortz, E, Garcia-Sastre, A, 2007-02-12 19:39:05
catalystActivity	[CatalystActivity:192665] RNA-directed 5'-3' RNA polymerase activity of Viral Polymerase [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:168327] 2007-04-16 22:35:07
dbId	168280
disease	[Disease:1660558] influenza
displayName	Priming and Initiation of Transcription
eventOf	[Pathway:R-HSA-168325] Viral Messenger RNA Synthesis - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-168301] Elongation, Polyadenylation and Termination - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:6686] viral transcription
input	[Complex:R-FLU-192703] vRNA Transcription Complex [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:169042] A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcription [LiteratureReference:192761] Priming of influenza viral RNA transcription by capped heterologous RNAs [LiteratureReference:169020] Recombinant influenza virus polymerase: requirement of both 5' and 3' viral ends for endonuclease activity [LiteratureReference:192844] The active sites of the influenza cap-dependent endonuclease are on different polymerase subunits
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Priming and Initiation of Transcription
output	[Complex:R-FLU-192756] Initiated vRNA Transcription Complex [nucleoplasm] [OtherEntity:R-ALL-193039] Mature intronless transcript derived mRNA with m7G cap removed [nucleoplasm]
precedingEvent	[Reaction:R-HSA-168326] Assembly of an Active Transcription Complex - Homo sapiens
relatedSpecies	[Species:9031716] Influenza A virus
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:193030] Squires, B, 2007-02-12 19:39:22
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-168280
summation	[Summation:168985] The host cell mRNA bound to viral RNA polymerase PB2 subunit...

Referrals

(hasEvent)	[Pathway:R-HSA-168325] Viral Messenger RNA Synthesis
(precedingEvent)	[BlackBoxEvent:R-HSA-168301] Elongation, Polyadenylation and Termination