Reactome | 2xN4GlycoAsn-TLR4 [plasma membrane]

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2xN4GlycoAsn-TLR4 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9707678] TLR4:Hemes:LY96 [plasma membrane] - Homo sapiens [Complex:R-HSA-166050] TLR4:LY96 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9707659] Hemes:LY96 activates TLR4 - Homo sapiens
created	[InstanceEdit:166046] de Bono, B, 2005-08-16 13:36:36
dbId	166045
displayName	2xN4GlycoAsn-TLR4 [plasma membrane]
endCoordinate	839
hasModifiedResidue	[ModifiedResidue:3322083] N4-glycosyl-L-asparagine at 526 [ModifiedResidue:3322088] N4-glycosyl-L-asparagine at 575
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-166045] Tlr4 [plasma membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-166045] Tlr4 [plasma membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-166045] TLR4 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-166045] TLR4 [plasma membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-166045] TLR4 [plasma membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-166045] tlr4bb [plasma membrane] - Danio rerio [EntityWithAccessionedSequence:R-GGA-166045] TLR4 [plasma membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-166045] MstProx [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-166045-2] Toll-4 [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DME-166045-3] Toll-9 [plasma membrane] - Drosophila melanogaster [DefinedSet:R-DME-166045-4] Homologues of 2xN4GlycoAsn-TLR4 [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-DDI-166045] 2xN4GlycoAsn-TLR4 [plasma membrane] - Dictyostelium discoideum
literatureReference	[LiteratureReference:3322089] MD-2 and TLR4 N-linked glycosylations are important for a functional lipopolysaccharide receptor
maxDepth	1
modified	[InstanceEdit:3632907] Wu, G, 2013-05-28
name	2xN4GlycoAsn-TLR4 TLR4
referenceEntity	[ReferenceGeneProduct:uniprot:O00206] UniProt:O00206 TLR4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-166045
startCoordinate	24
updateTrackers	[UpdateTracker:9880597] Update Tracker - [EntityWithAccessionedSequence:166045] 2xN4GlycoAsn-TLR4 [plasma membrane] - v45:[addHasModifiedResidue, addLiteratureReference, addName] [UpdateTracker:9867021] Update Tracker - [EntityWithAccessionedSequence:166045] 2xN4GlycoAsn-TLR4 [plasma membrane] - v25:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9880597] Update Tracker - [EntityWithAccessionedSequence:166045] 2xN4GlycoAsn-TLR4 [plasma membrane] - v45:[addHasModifiedResidue, addLiteratureReference, addName] [UpdateTracker:9867021] Update Tracker - [EntityWithAccessionedSequence:166045] 2xN4GlycoAsn-TLR4 [plasma membrane] - v25:[modifyName]
(hasComponent)	[Complex:R-HSA-9707678] TLR4:Hemes:LY96 [plasma membrane] [Complex:R-HSA-8869699] TLR4:TLR6 [plasma membrane] [Complex:R-HSA-166050] TLR4:LY96 [plasma membrane]
(input)	[Reaction:R-HSA-9707659] Hemes:LY96 activates TLR4

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