Reactome | Expression of TM7SF2

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Expression of TM7SF2 Show undefined attributes

authored	[InstanceEdit:1655770] May, B, 2011-09-28
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:1655841] May, B, 2011-10-13
dbId	1655833
displayName	Expression of TM7SF2
edited	[InstanceEdit:1655770] May, B, 2011-09-28
eventOf	[Pathway:R-HSA-2426168] Activation of gene expression by SREBF (SREBP) - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:17788] positive regulation of transcription by RNA polymerase II
input	[EntityWithAccessionedSequence:R-HSA-2393984] TM7SF2 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1655695] Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box
maxDepth	1
modified	[InstanceEdit:9961220] D'Eustachio, Peter, 2025-07-21
name	Expression of TM7SF2
output	[EntityWithAccessionedSequence:R-HSA-194710] TM7SF2 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-HSA-2065966] SREBP1A,1C,2 binds the TM7SF2 promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-1655859] Positive gene expression regulation by 'SREBP1A,1C,2:NF-Y:TM7SF2 gene [nucleoplasm]'
regulationReference	[RegulationReference:9642328] Positive gene expression regulation by 'SREBP1A,1C,2:NF-Y:TM7SF2 gene [nucleoplasm]' Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box
releaseDate	2012-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2457630] Liang, Guosheng, 2012-08-25
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-1655833
summation	[Summation:1655779] The TM7SF2 gene is transcribed to yield mRNA and the mRNA i... [Summation:1655816] SREBF2 (SREBP2) binds the promoter of the TM7SF2 gene and en...
updateTrackers	[UpdateTracker:9775741] Update Tracker - [BlackBoxEvent:1655833] Expression of TM7SF2 - v78:[addSummation] [UpdateTracker:9782034] Update Tracker - [BlackBoxEvent:1655833] Expression of TM7SF2 - v60:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9775741] Update Tracker - [BlackBoxEvent:1655833] Expression of TM7SF2 - v78:[addSummation] [UpdateTracker:9782034] Update Tracker - [BlackBoxEvent:1655833] Expression of TM7SF2 - v60:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-2426168] Activation of gene expression by SREBF (SREBP)