Expression of TM7SF2

Stable Identifier
R-HSA-1655833
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, endoplasmic reticulum membrane
ReviewStatus
5/5
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Expression of TM7SF2
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The TM7SF2 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. SREBF2 (SREBP2) binds the promoter of the TM7SF2 gene and enhances transcription (Bennati et al. 2006, Schiavone et al. 2010).
Literature References
PubMed ID Title Journal Year
20138239 Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box

Schiavoni, G, Bennati, AM, Castelli, M, Fazia, MA, Beccari, T, Servillo, G, Roberti, R

Biochim Biophys Acta 2010
Participants
Input
Output
Participates
as an event of
Event Information
Go Biological Process
positive regulation of transcription by RNA polymerase II (0045944)
This event is regulated
Positively by
Regulator
SREBP1A,1C,2:NF-Y:TM7SF2 gene [nucleoplasm] (Homo sapiens)
Authored
May, B  (2011-09-28)
Reviewed
Liang, G  (2012-08-26)
Created
May, B  (2011-10-13)
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