Reactome | FGFR2 S267P [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

FGFR2 S267P [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2033335] FGFR2 S267P mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2033335] FGFR2 S267P mutant dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:1637921] Rothfels, K, 2011-10-05
crossReference	[DatabaseIdentifier:12021291] Mondo:0007405
dbId	1637920
disease	[Disease:1500687] stomach cancer [Disease:1625203] Crouzon syndrome [Disease:1500689] cancer [Disease:2032940] bone development disease
displayName	FGFR2 S267P [plasma membrane]
endCoordinate	821
hasModifiedResidue	[ReplacedResidue:1637922] L-serine 267 replaced with L-proline
inDisease	true
literatureReference	[LiteratureReference:1637923] Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers [LiteratureReference:2029801] Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand [LiteratureReference:2029815] Mutations in the third immunoglobulin domain of the fibroblast growth factor receptor-2 gene in Crouzon syndrome
maxDepth	1
memberOf	[CandidateSet:R-HSA-2029955] FGFR2 ligand-independent mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:5649535] Rothfels, Karen, 2014-11-20
name	FGFR2 S267P
referenceEntity	[ReferenceGeneProduct:uniprot:P21802] UniProt:P21802 FGFR2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1637920
startCoordinate	22
updateTrackers	[UpdateTracker:9890608] Update Tracker - [EntityWithAccessionedSequence:1637920] FGFR2 S267P [plasma membrane] - v52:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9890608] Update Tracker - [EntityWithAccessionedSequence:1637920] FGFR2 S267P [plasma membrane] - v52:[modifyName]
(hasComponent)	[Complex:R-HSA-2033335] FGFR2 S267P mutant dimer [plasma membrane]
(hasMember)	[CandidateSet:R-HSA-2029955] FGFR2 ligand-independent mutants [plasma membrane]

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