Reactome | FGFR2c A315T [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

FGFR2c A315T [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-HSA-2033375] FGFR2c mutants with enhanced ligand binding [plasma membrane] - Homo sapiens
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-2071934] FGFR2c A315T mutant dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-2071934] FGFR2c A315T mutant dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:1637892] Rothfels, K, 2011-10-05
crossReference	[DatabaseIdentifier:12020811] Mondo:0002480 [DatabaseIdentifier:2033278] COSMIC:COSV60645182
dbId	1637889
disease	[Disease:1614674] female reproductive endometrioid cancer [Disease:1500689] cancer
displayName	FGFR2c A315T [plasma membrane]
endCoordinate	821
hasModifiedResidue	[ReplacedResidue:1637890] L-alanine 315 replaced with L-threonine
inDisease	true
literatureReference	[LiteratureReference:1637891] Frequent activating FGFR2 mutations in endometrial carcinomas parallel germline mutations associated with craniosynostosis and skeletal dysplasia syndromes
maxDepth	1
modified	[InstanceEdit:5649553] Rothfels, Karen, 2014-11-20
name	FGFR2c A315T FGFR2-1 A315T
referenceEntity	[ReferenceIsoform:uniprot:P21802-1] UniProt:P21802-1 FGFR2
referenceType	ReferenceIsoform
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-1637889
startCoordinate	22
updateTrackers	[UpdateTracker:9892002] Update Tracker - [EntityWithAccessionedSequence:1637889] FGFR2c A315T [plasma membrane] - v52:[modifyName] [UpdateTracker:9881398] Update Tracker - [EntityWithAccessionedSequence:1637889] FGFR2c A315T [plasma membrane] - v45:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9892002] Update Tracker - [EntityWithAccessionedSequence:1637889] FGFR2c A315T [plasma membrane] - v52:[modifyName] [UpdateTracker:9881398] Update Tracker - [EntityWithAccessionedSequence:1637889] FGFR2c A315T [plasma membrane] - v45:[addName]
(hasCandidate)	[CandidateSet:R-HSA-2033375] FGFR2c mutants with enhanced ligand binding [plasma membrane]
(hasComponent)	[Complex:R-HSA-2071934] FGFR2c A315T mutant dimer [plasma membrane]

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