Reactome | SQR oxidizes sulfide to bound persulfide

Schema > Reaction > Entries

SQR oxidizes sulfide to bound persulfide Show undefined attributes

authored	[InstanceEdit:1237120] Stephan, R, 2010-10-24
catalystActivity	[CatalystActivity:1614554] sulfide:quinone oxidoreductase activity of SQR:FAD [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:70101] cytosol
created	[InstanceEdit:1614621] Jassal, Bijay, 2011-09-29
dbId	1614665
displayName	SQR oxidizes sulfide to bound persulfide
edited	[InstanceEdit:1614621] Jassal, Bijay, 2011-09-29
eventOf	[Pathway:R-HSA-1614517] Sulfide oxidation to sulfate - Homo sapiens
followingEvent	[Reaction:R-HSA-1614605] Persulfide sulfur is dioxygenated - Homo sapiens [Reaction:R-HSA-1614618] Persulfide sulfur is transferred onto sulfite - Homo sapiens
inferredFrom	[Reaction:R-AMA-1614571] Sqr oxidizes sulfide to bound persulfide - Arenicola marina
input	2 × [EntityWithAccessionedSequence:R-HSA-1614613] 2xHC-SQRDL(1-450) [mitochondrial inner membrane] 2 × [SimpleEntity:R-ALL-73663] CoQ [mitochondrial inner membrane] 4 × [SimpleEntity:R-ALL-1614597] H+ [mitochondrial inner membrane] 2 × [SimpleEntity:R-ALL-1614532] H2S [cytosol]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:1614522] Single eubacterial origin of eukaryotic sulfide:quinone oxidoreductase, a mitochondrial enzyme conserved from the early evolution of eukaryotes during anoxic and sulfidic times [LiteratureReference:1614578] Three enzymatic activities catalyze the oxidation of sulfide to thiosulfate in mammalian and invertebrate mitochondria
maxDepth	1
modified	[InstanceEdit:9930119] D'Eustachio, Peter, 2024-12-02
name	SQR oxidizes sulfide to bound persulfide
output	2 × [EntityWithAccessionedSequence:R-HSA-1614576] CysS-SQRDL(1-450) [mitochondrial inner membrane] 2 × [SimpleEntity:R-ALL-76633] QH2 [mitochondrial inner membrane]
precedingEvent	[Reaction:R-HSA-1614614] Cysteine is degraded to pyruvate and H2S - Homo sapiens [Reaction:R-HSA-1614591] Excess cysteine yields lanthionine and H2S - Homo sapiens [Reaction:R-HSA-1614567] Excess homocysteine yields homolanthionine and H2S - Homo sapiens [Reaction:R-HSA-1614631] Homocysteine is degraded to oxobutanoate and H2S - Homo sapiens
releaseDate	2011-12-06
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:1660489] D'Eustachio, P, 2011-10-13
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-1614665
summation	[Summation:1614512] When SQR is in the oxidized state, it can bind hydrogen sulf...

Referrals

(hasEvent)	[Pathway:R-HSA-1614517] Sulfide oxidation to sulfate
(precedingEvent)	[Reaction:R-HSA-1614605] Persulfide sulfur is dioxygenated [Reaction:R-HSA-1614618] Persulfide sulfur is transferred onto sulfite
(inferredTo)	[Reaction:R-AMA-1614571] Sqr oxidizes sulfide to bound persulfide