SQR oxidizes sulfide to bound persulfide

Stable Identifier
R-HSA-1614665
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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When SQR is in the oxidized state, it can bind hydrogen sulfide as persulfide to one of its own cysteine residue, the electrons being transferred to ubiquinone. After that the additional sulfur is dioxygenated by another enzyme (ETHE1). The activity of human SQR was deduced from the orthologue in Arenicola marina (Theissen et al. 2003, Hildebrandt & Grieshaber 2008).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
sulfide:quinone oxidoreductase activity of SQR:FAD [mitochondrial inner membrane]
Physical Entity
Activity
Inferred From
Authored
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Created