Reactome | FBXW7 R505/387L mutant [nucleoplasm]

Schema > CandidateSet > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:1602437] Orlic-Milacic, M, 2011-09-14
crossReference	[DatabaseIdentifier:12020841] Mondo:0004963 [DatabaseIdentifier:2220839] COSMIC:COSV55908371
dbId	1602442
disease	[Disease:1485587] T-cell acute lymphoblastic leukemia [Disease:1500689] cancer
displayName	FBXW7 R505/387L mutant [nucleoplasm]
hasCandidate	[EntityWithAccessionedSequence:R-HSA-1602440] FBXW7gamma R387L [nucleoplasm] - Homo sapiens
hasMember	[EntityWithAccessionedSequence:R-HSA-1602439] FBXW7alpha R505L [nucleoplasm] - Homo sapiens
inDisease	true
literatureReference	[LiteratureReference:1602435] The SCFFBW7 ubiquitin ligase complex as a tumor suppressor in T cell leukemia
maxDepth	2
memberOf	[DefinedSet:R-HSA-1602340] FBXW7 WD mutants [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:2220840] Orlic-Milacic, M, 2012-05-01
name	FBXW7 R505/387L mutant FBXW7 Arg505/387Leu mutant
schemaClass	CandidateSet
species	[Species:48887] Homo sapiens
stId	R-HSA-1602442

(hasMember)

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