Reactome | ACSM2B-like proteins transform ST to ST-CoA

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ACSM2B-like proteins transform ST to ST-CoA Show undefined attributes

authored	[InstanceEdit:159568] Jassal, B, 2005-03-11 11:56:39
catalystActivity	[CatalystActivity:159441] CoA-ligase activity of ACSM2B-like proteins [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:159568] Jassal, B, 2005-03-11 11:56:39
crossReference	[DatabaseIdentifier:11881315] Rhea:61669
dbId	159567
displayName	ACSM2B-like proteins transform ST to ST-CoA
eventOf	[Pathway:R-HSA-177128] Conjugation of salicylate with glycine - Homo sapiens
followingEvent	[Reaction:R-HSA-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-159559] ST [mitochondrial matrix]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:159555] Pharmacokinetics of salicylate elimination in man [LiteratureReference:159552] Isolation, sequencing, and expression of a cDNA for the HXM-A form of xenobiotic/medium-chain fatty acid:CoA ligase from human liver mitochondria
modified	[InstanceEdit:11879863] Wright, Adam, 2024-03-11
name	ACSM2B-like proteins transform ST to ST-CoA salicylate + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate Salicylic acid and Coenzyme A react to form salicylate-CoA thioester
orthologousEvent	[Reaction:R-GGA-159567] ACSM2B-like proteins transform ST to ST-CoA - Gallus gallus [Reaction:R-XTR-159567] ACSM2B-like proteins transform ST to ST-CoA - Xenopus tropicalis [Reaction:R-DRE-159567] ACSM2B-like proteins transform ST to ST-CoA - Danio rerio [Reaction:R-SSC-159567] ACSM2B-like proteins transform ST to ST-CoA - Sus scrofa [Reaction:R-BTA-159567] ACSM2B-like proteins transform ST to ST-CoA - Bos taurus [Reaction:R-CFA-159567] ACSM2B-like proteins transform ST to ST-CoA - Canis familiaris [Reaction:R-RNO-159567] ACSM2B-like proteins transform ST to ST-CoA - Rattus norvegicus [Reaction:R-MMU-159567] ACSM2B-like proteins transform ST to ST-CoA - Mus musculus
output	[SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix] [SimpleEntity:R-ALL-159557] ST-CoA [mitochondrial matrix]
releaseDate	2006-04-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:351775] D'Eustachio, P, 2008-05-28 08:30:54
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-159567
summation	[Summation:177159] Salicylate (ST) and ATP react with coenzyme A to form salicy...

Referrals

(hasEvent)	[Pathway:R-HSA-177128] Conjugation of salicylate with glycine
(precedingEvent)	[Reaction:R-HSA-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA

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