Reactome | ACSM2B-like proteins transform ST to ST-CoA

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ACSM2B-like proteins transform ST to ST-CoA Show undefined attributes

catalystActivity	[CatalystActivity:9992054] CoA-ligase activity of ACSM2B-like proteins [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	9992056
displayName	ACSM2B-like proteins transform ST to ST-CoA
eventOf	[Pathway:R-RNO-177128] Conjugation of salicylate with glycine - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-159567] ACSM2B-like proteins transform ST to ST-CoA - Homo sapiens
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-159559] ST [mitochondrial matrix]
isInDisease	false
isInferred	true
name	ACSM2B-like proteins transform ST to ST-CoA salicylate + Coenzyme A + ATP => salicylate-CoA + AMP + pyrophosphate Salicylic acid and Coenzyme A react to form salicylate-CoA thioester
output	[SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix] [SimpleEntity:R-ALL-159557] ST-CoA [mitochondrial matrix]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-159567
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-177128] Conjugation of salicylate with glycine
(precedingEvent)	[Reaction:R-RNO-159574] GLYAT-like proteins transfer glycine to ST-CoA to form SUA
(inferredTo)	[Reaction:R-HSA-159567] ACSM2B-like proteins transform ST to ST-CoA

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